Learning objectives
As part of the integrated course, the course aims to provide the knowledge necessary for the understanding of disease processes from a molecular and cellular point of view. The knowledge gained will enable students to correlate molecular alterations with microscopic and macroscopic alterations observable in cells, tissues and organs, in order to fully understand the pathogenesis of the disease. Bibliographical references may be used to acquire independent judgment, communication skills and learning ability, which can be demonstrated during the examination.
Prerequisites
It is advised to have supported the examinations of the previous year.
Course unit content
The course will concern on the following contents:
Mechanism of response to injury (inflammation, homeostasis, tissue repair), Cell death; Tumors; Blood disorders; haemostasis and its alterations; Immunity.
Full programme
General Pathology and Physiopatology:
Cellular Pathology: Cellular alterations of growth and differentiation. Hyperplasia, hypertrophy, atrophy, metaplasia, dysplasia. Necrosis and apoptosis.
Oncology: classification and nomenclature of tumors; Benignant and malignant tumors; Fundamentals in molecular oncology; invasivity and metastasis; pathogenesis of neoplastic diseases. Grading and staging.
The blood: composition, cells, general pathophysiology. Anemia and Thalassemia syndromes. Leukemia and lymphoma. Phases and event of the
haemostatic response. Hemorrhagic disorders; thrombosis and embolism; infarction.
Inflammation: events of acute inflammation; the exudate; types of exudate; phagocytosis; chronic inflammation and granulomas; chemical mediators
of inflammation; systemic effects of inflammation and fever; tissue repair.
Immunology:
General features of innate and adaptive immunity.
Bibliography
Patologia Generale e Fisiopatologia per le professioni sanitarie Jeanette Anne Marie Maier, McGraw Hill, II ed.
Patologia Generale ed Elementi di Fisiopatologia Maurizio Parola, EdiSES, II ed.
Teaching methods
The course will be conducted through interactive lectures in front of the students, with the aid of illustrative material collected in PowerPoint files that, at the end of the course, will be made available to students.
During the lectures the main concepts of each topic will be exposed, encouraging students to ask questions on the basis of references that will be provided.
Assessment methods and criteria
Learning outcomes will be verified through an oral examination. Questions on the topics relating to the course will be used to test knowledge and
understanding of the student in the scientific discipline, and her/his ability to apply such knowledge and understanding in occupational contexts.
Other information
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