Learning objectives
Know the principles and procedures of Evidence Based Practice
Know methods amd tools to design clinical research
Classify biomedical information sources
Know the disegn, objectives and main bias of observational and sperimental studies
Learn the rules and tools to improve the quality of clinical research
Learn methods and tools of the process "from the research question to the disegn of the study"
Know and use the major biomedical databases
Course unit content
* Classification of health research and of biomedical information
* Architecture and quality of clinical research
* Rules and tools to improve quality of clinical research
* From the research question to the disegn of the study
Full programme
* Classification of Health Research
Objectives and areas of: Basic Research, Clinical Research; Health Service Research, Qualitative Research, Educational Research
* Classification of biomedical information
Primary Sources: observational and sperimental studies
Secondary Sources: systematic reviews, guidelines, HTA reports, economic analysis, decision making
Opinion-based sources
* Architecture of clinical research
Observational and sperimental studies: disegn, objectives and main bias
*Quality of clinical reserach
Methodological standards in the planning, management, analysis and reporting phases
Size of critical appraisal: internal validity, clinical relevance, applicability, consistency.
Ethics, integrity and social value
* Rules and tools to improve quality of clinical research
Statement of International Committee of Medical Journal Editors
Ethical committees
Trial registers
EQUATOR network and reporting guidelines: CONSORT; STARD; STROBE, etc.
* From the research question to the disegn of the study
Define the objective of the study
Structuring the research question: EPICOT model
Carry out a systemativ review of published and ongoing studies:
- Primary databases: MEDLINE, EMBASE, CINHAL
- Systematic review databases:
Cochrane Database of Systematic Reviews (CDSR),
Database of Abstract of Reviews of Effects (DARE), Trials (mRCT, ClinicalTrials.gov) and Systematic Review (PROSPERO) registers
* Verify the relevance of the research question in relation to available evidence
* Refine the research question
Choose the most appropriate study disegn
Bibliography
Didactic material provided by the teacher
Teaching methods
Theoretical lessons, practical demonstration, student group work, practical activities
