Learning objectives
As part of the integrated course, the course aims to provide the knowledge necessary for the understanding of disease processes from a molecular and cellular point of view. The knowledge gained will enable students to correlate molecular alterations with microscopic and macroscopic alterations observable in cells, tissues and organs, in order to fully understand the pathogenesis of the disease. Bibliographical references may be used to acquire independent judgment, communication skills and learning ability, which can be demonstrated during the examination.
Prerequisites
It is advised to have supported the examinations of the previous year.
Course unit content
The course will concern on the following contents:
Mechanism of response to injury (inflammation, homeostasis, tissue repair), Cell death; Tumors; Blood disorders; haemostasis and its alterations; Immunity.
Full programme
General Pathology and Physiopatology:
Cellular Pathology: Cellular alterations of growth and differentiation. Hyperplasia, hypertrophy, atrophy, metaplasia, dysplasia. Necrosis and apoptosis.
Oncology: classification and nomenclature of tumors; Benignant and malignant tumors; Fundamentals in molecular oncology; invasivity and metastasis; pathogenesis of neoplastic diseases. Grading and staging.
The blood: composition, cells, general pathophysiology. Anemia and Thalassemia syndromes. Leukemia and lymphoma. Phases and event of the
haemostatic response. Hemorrhagic disorders; thrombosis and embolism; infarction.
Inflammation: events of acute inflammation; the exudate; types of exudate; phagocytosis; chronic inflammation and granulomas; chemical mediators
of inflammation; systemic effects of inflammation and fever; tissue repair.
Immunology:
General features of innate and adaptive immunity.
Bibliography
Patologia Generale e Fisiopatologia per le professioni sanitarie Jeanette Anne Marie Maier, McGraw Hill, II ed.
Patologia Generale ed Elementi di Fisiopatologia Maurizio Parola, EdiSES, II ed.
Teaching methods
The course will be conducted through interactive lectures in front of the students, with the aid of illustrative material trying to involve the student so that it can be an active part of the lesson.
During the lectures the main concepts of each topic will be exposed, encouraging students to ask questions on the basis of references that will be provided.
Assessment methods and criteria
Verification tests in progress will not be carried out.
Learning outcomes will be verified through an oral examination. Questions on the topics relating to the course will be used to test knowledge and
understanding of the student in the scientific discipline, and her/his ability to apply such knowledge and understanding in occupational contexts.
Each student will be asked two questions on topics listed in the extended program. The inability to answer a question (or at least ascertained inability to provide a correct definition of the pathological phenomenon subject of the application) will result in not passing the exam.
At the end of the answer the teacher will formulate a judgment given in brackets:
A. Excellent knowledge and understanding of the topic. High capacity for applying knowledge in bio-medical problems. Vote of thirty: 30.
B. Good knowledge and understanding of the topic. Good ability to apply knowledge in bio-medical problems. Vote of thirty: 27-29.
C. Good knowledge and understanding of the topic. Demonstrated ability to apply the knowledge in bio-medical problems. Vote of thirty: 24-26.
D. Knowledge and understanding of the fully sufficient. Fair ability to apply the knowledge in bio-medical problems. Vote of thirty: 21-23.
E. Knowledge and understanding of the subject just enough with obvious gaps. Poor ability to apply knowledge in bio-medical problems. Vote of thirty: 18-20.
Laud will be proposed for the demonstration of independence of judgment, high communication skills and ability to learn independently.
Other information
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2030 agenda goals for sustainable development
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