PHARMACOLOGY
cod. 21971

Academic year 2017/18
2° year of course - First semester
Professor
POZZOLI Cristina
Academic discipline
Farmacologia (BIO/14)
Field
Scienze medico chirurgiche
Type of training activity
Characterising
14 hours
of face-to-face activities
2 credits
hub: -
course unit
in ITALIAN

Integrated course unit module: GENERAL PATHOLOGY, PHARMACOLOGY AND MICROBIOLOGY

Learning objectives

Knowledge of principles of general pharmacology. Knowledge of neuromuscolar drugs, of drugs used for central and pheripheral nervous system, and of drugs for osteoarticular disease.
Capability of applying knowledge to conditions of interest for the physiotherapist.

Prerequisites

Adequate bases of biology, chemistry, biochemistry, physics, anatomy

Course unit content

Elements of general pharmacology: pharmacodynamics and pharmacokinetics. Factors modifying drug response. Drug toxicity. Special pharmacology: neuromuscolar drugs, pain therapy, antiinflammatory drugs, antirheumatic and antigout drugs.

Full programme

General pharmacology. What is pharmacology. Drugs. Basic pharmacodynamics: sites and mechanisms of action, agonists and antagonists, the dose-effect relationship.
Basic pharmacokinetics: how drugs reach their site of action, routes of administration, drug adsorption. Drug-protein binding and drug biodistribution.
Drug biotransformation. Drug excretion. Pharmacokinetic parameters: bioavailability, apparent distribution volume, plasma drug half-life, clearance. Conditions modifying drug effects: drug interactions, the importance of patient conditions. Tolerance and resistance. Drug toxicity: collateral and unwanted events.
Special pharmacology:
Neuromuscular drugs: depolarizing and competitive blocking agents, botulinum, central (GABAergic) and preripheral myorelaxant agents. Drugs for myasthenia gravis: anticholinesterase drugs, steroids, immunosuppressant drugs.
Anti-Parkinson agents.
Analgesic drugs: opiates and non-opiate analgesics; local anesthetics.
Antiinflammatory drugs: NSAIDs, steroids (glucocorticoids).
Antirheumatic drugs (DMARDs), antigout drugs (colchicine, allopurinol, uricosuric agents). Drugs used in bone disorders: Vitamin D, calcitonin and bisphosphonates.
Drugs for Arthrosis: condroprotective drugs.

Bibliography

PC Panus, B Katzung, EE Jobst, SL Tinsley, SB Master, AJ Trevor.
"Farmacologia in Riabilitazione" Ed. Italiana a cura di V. Locatelli 2014.
Dale, Haylett "Elementi di farmacologia" Compendio per l'esame. Ed. Mediche Scientifiche Internazionali EMSI;
Clark M.A.; Finkel R. "Le basi della farmacologia" 2° Edizione Italiana dalla 5° edizione americana, Zanichelli Editore, 2013.
Didactic resources used during lessons (ie, power point slides) have to be considered integral part of the reference bibliography; they will be available on the Elly site, on the course page.

Teaching methods

Interactive oral lessons

Assessment methods and criteria

No interim evaluation is programmed. The final evaluation will consist in an oral examination in which the student will discuss one of the subjects of the extended program.

Other information

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