Learning objectives
To give students of the magistral degree in Physics (biophysical-medical curriculum) some basic concepts of the molecular mechanisms of transmission and implementation of genetic information.
Course unit content
Part 1: Proteins: Composition and structure; Purification and structural analysis; Analysis of function: the case of hemoglobin; Enzymes: concepts of enzymatic catalysis and examples.<br />
Part 2: Nucleic Acids: Flow of information; Analysis of genomes and molecular evolution; DNA: replication, damage and repair; RNA: transcription and maturation; Proteins: translation, transport and degradation.
Bibliography
J:M: Berg, J.L. Tymoczko, L. Stryer: Biochemistry, VI ed., W.H. Freeman 2006.<br />
G.A. Petsko and D. Ringe: Protein Structure and Function, New Science Press 2004.<br />
J.D. Watson et al.: Molecular Biology of the Gene, VI ed., CSHL Press 2008.