cod. 1000190

Academic year 2009/10
1° year of course - First semester
Academic discipline
Patologia generale (MED/04)
Discipline biotecnologiche comuni
Type of training activity
8 hours
of face-to-face activities
1 credits
hub: -
course unit
in - - -

Integrated course unit module: THE MOLECULAR MECHANISMS OF DISEASE

Learning objectives

To provide the bases for the comprehension of biologic propertes of tumors and the molecular basis of carcinogenesis.


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Course unit content

<p>Cancer stem cells and cancer cell lineages</p>
<p>Molecular basis of cancer: <br />
<br />
Essential alterations for malignant transformation <br />
<br />
Self-sufficiency in growth signals: oncogenes</p>
<p>Insensitivity to growth inibition and escape from senescence: tumor suppressor genes</p>
<p>Evasion from apoptosis</p>
<p>Invasion and metastasis</p>
<p>Genomic instability </p>
<p> </p>
<p> <br />

Full programme

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No specific text is adopted. Proper reference to the texts of biochemistry and cell biology used in previous courses is recommended. Lectures will be supported by slides and scientific literature, which will be provided to the students.

Teaching methods

Oral lessons (slides and scientific literature will be used during the lessons) . <br />
The tutorials will be provided to the students. <br />
Oral examination (with discussion of scientific literature). <br />

Assessment methods and criteria

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Other information

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