CLINICAL BIOCHEMISTRY
cod. 21328

Academic year 2023/24
1° year of course - Second semester
Professor
- Thelma PERTINHEZ
Academic discipline
Biochimica clinica e biologia molecolare clinica (BIO/12)
Field
"altre attività quali l'informatica, attività seminariali ecc."
Type of training activity
More
10 hours
of face-to-face activities
1 credits
hub: -
course unit
in ITALIAN

Integrated course unit module: BIOMEDICAL SCIENCES II

Learning objectives

Learning laboratory organization to the purpose of a proper interactions between facilities (hospital ward-lab). Learning of analytical procedures steps, with particular focus to the preanalytical phase (sample collection, storage, processing and transporting biological samples). Acquiring knowledge on the main clinical biochemistry analyses and execution approaches of the analytical processes). Acquiring knowledge on the main diagnostic profiles, with special focus on pregnancy screenings which can be requested.

Prerequisites

- - -

Course unit content

Laboratory organization. The analytical phase. The biological sample. Types of interference. Types of clinical biochemistry tests and analytical approaches. Analytical profiles of functionality or of injuries to major organs and systems. Analytical profiles during pregnancy.

Full programme

The diagnostic laboratory process: organizational elements. The preanalytical phase: patient preparation, sample’s collection, treatment and storage. Clinical chemistry laboratory analysis: spectrophotometry and potentiometry. Calibrations. Immunochemistry principles. Quality of the results. Internal and external quality control. reference intervals. Laboratory analysis during pregnancy: screening tests and diagnostic tests. Presentation of the main diagnostical profiles. Hematological diagnostic parameters. Thyroid and pregnancy. Main enzymatic determinations and related clinical use.
Biomarkers of cardiac functionality. Laboratory indexes of functional and ischemic damage. Parameters of hepatic and renal functionality.

Bibliography

M.Ciaccio, G.Lippi. Biochimica Clinica e Medicina di Laboratorio. EdiSES (2017).
M. Ciaccio. Elementi di Biochimica Clinica e Medicina di Laboratorio. Edises (2020)
Ministero della salute: Linee Guida della gravidanza fisiologica (2011).
Linee guida per lo screening prenatale della trisomia 21.

Teaching methods

According to the regulation of the Italian Government and the University of Parma about the COVID-19 pandemics, the present course is realized with frontal lessons via mixed in-presence and at-distance modality. In particular, the teacher takes lessons in the classroom with the help of PC (Powerpoint slides); simultaneous connection of the PC to the Teams platform in streaming modality ensures connection with students not present in the classroom. Each lesson is registered and loaded in the Elly portal of the course, together with the slides. The teacher is available for further explanations in office or by distance via Teams after e-mail appointment, or via chat on Elly platform.

Assessment methods and criteria

The achievement of the learning tasks will be assessed by an oral / written evaluation related to the covered topics. The questions will assess students’ knowledge and understanding of the contents, and if he is able to apply the knowledge acquired in the practice of the profession. Failed answer to one or more questions or proved insufficiency of the basic knowledge on the subject will preclude the successful completion of the exam. In case of completion of the exam, an evaluation that contributes to the final grade of the course will be defined and it will be based on the achievement of the objectives.

Other information