SUSTAINABLE USE OF DRUGS IN ANIMALS AND EXPERIMENTAL MODELS
cod. 1009076

Academic year 2022/23
2° year of course - Second semester
Professor
BERTINI Simone, MENOZZI Alessandro
Academic discipline
Farmacologia e tossicologia veterinaria (VET/07)
Field
A scelta dello studente
Type of training activity
Student's choice
14 hours
of face-to-face activities
2 credits
hub: PARMA
course unit
in ITALIAN

Learning objectives

At the end of the course the student should have acquired knowledge regarding general and special toxicology. In detail, the student should be able to:
1. Know the mechanisms of action by which a xenobiotic can be found as a residue in animal foods. Know the most important classes of residues and contaminants. Be able to employ the specific language of discipline and appropriate scientific terminology. (knowledge and comprehension)
2. Understand the toxic properties of xenobiotic residues. (applying knowledge and understanding)
3. Be able to clearly explain the results of studies and the characteristics of a residue or contaminant even to a non-expert audience. (communication skills)
4. Know how to assess the presence of a certain residue based on acquired knowledge and clinical needs. (making judgment)
5. Link the different topics treated in the course among themselves and to other disciplines of the academic degree course. (learning skills).
The student should have also acquired knowledge regarding the sustainable use of drugs in animals, and some methods for the study of drug effects in experimental models of pharmacodynamics. In detail, the student should be able to:
1. Know the principles of sustainable use of drugs in animals. Know the basic techniques for the study of drug effects in experimental models in vitro. Be able to employ the appropriate scientific language and terminology. (knowledge and understanding)
2. Understand the importance and implications of the sustainable use of drugs in animals, and the basic concepts behind the application of in vitro experimental models for the study of drug effects (applying knowledge and understanding)
3. Be able to explain the acquired notions and the results of the studies also to an audience of non-experts. (communication skills)
4. Be able choose the most appropriate drug in the view of a sustainable use of therapeutic compounds, and to select a suitable experimental model for the study of drug effects on the basis of the acquired knowledge. (making judgements)
5. Link the different topics treated in the course between themselves and with other disciplines of the academic degree course. (learning skills)

Prerequisites

As per Degree Course. Please refer to https://cdlm-bmvf.unipr.it/it

Course unit content

The Course will provide students with the essential concepts of the Toxicology of residues and contaminants; They will be dealt with topics concerning drug residues in food, their Italian and EU legislation, how to register a veterinary drug, the use of drugs in aquaculture and their residues, residues in honey and eggs, drugs granted for use in animals and those prohibited, the main environmental pollutants (dioxins, polychlorobiphenols, organochlorate, heavy metals, mycotoxins, growth promoters). The concept of MRL, suspension time, ADI is explained to the students; examples of the calculation of MRL of a residue will take place in classroom and in the computer lab. Moreover, students will be asked to browse the EMA website to search information on drug residues during practice lessons.
The Course provides the students with essential concepts to acquire basic knowledge about:
- experimental models of intestinal inflammation.
- methods of evaluation and measurement of intestinal damage "score" and other parameters of intestinal inflammation (myeloperoxidase, lipid peroxidation).
- methods for the study of the motility in vitro in normal and pathologic intestine.

Full programme

Please refer to the Section "Contenuti del Corso"

Bibliography

"Residui di farmaci e contaminanti ambientali nelle produzioni animali", a cura del prof. Carlo Nebbia, Edises Editrice.
Students can download pdf files of the lessons from Elly Platform.
The students are, however, reminded that the textbook must be integrated with classroom lectures.

Teaching methods

Frontal lessons

Assessment methods and criteria

The evaluation of the knowledge acquired by the student in the course is made by means of written exam. The student, therefore, after online registration to the official exam calendar published on the Department website, will have to take a written test composed by multiple-choice questions regarding topics of the course cited above. The student will have to show to have understood the core concepts of the treated topics of the course.

Specific support methods are provided for students with SLD, SEN or disabilities. They must send requests to be able to take advantage of compensatory and / or dispensatory measures during the examination at least 10 working days before the date scheduled for the examination by e-mail addressed to the teacher in charge of the course and in cc to the Department Coordinator ( list of contact persons and related email addresses available here http://cai.unipr.it/it/student-con-dsa-e-con-bes/42/) and at the Reception and Inclusion Center (cai@unipr.it).

The exam is carried out online via the TEAMS platform in the event of a recurrence of the Covid-19 pandemic.

Other information

9 examination sessions are scheduled throughout the academic year, as reported on ESSE3 platform website. 5 more sessions are scheduled for so called "fuori corso e ripetenti" students. A minimun of 14 days is required between two subsequent examination sessions. The examining board consists of at least two teachers.