KNOWLEDGE AND UNDERSTANDING
The main goal of the course is to provide students with the tools necessary for a detailed and critique analysis of the structure of proteins and their macromolecular complexes. The first part of the course is dedicated to the understanding of the physical-chemical properties of the amino acids and their interaction within a protein. During the second part of the course, students are challenged with practical exercises on the structural analysis of protein models by means of open source software.
APPLYING KNOWLEDGE AND UNDERSTANDING
The educational objective of the course is to achieve the necessary knowledge for a critical analysis of the structure of proteins and nucleic acids. By the end of the course students will have acquired the skills necessary to deal with the analysis and experimental study of biological macromolecules. They will learn how to retrive protein and nucleic acid coordinates from the PDB database, recognize the fold and use sofware for a detailed analysis of their structure.
The course is aimed at increasing the ability to critically analyze the structure of proteins, nucleic acids and their interactions.
The course includes significant activity of classroom discussion aimed at developing the ability of students to transfer skills acquired in support of their arguments. In the final exam, students must take an oral presentation on the structure and function of an assigned protein.
The many advancements of scientific research, particularly in the field of molecular biology require a continuous updating of skills. For this reason, the course aims to provide the necessary tools to achieve a wider knowledge and to align skills to the advancement in molecular biology research.