- Acquire knowledge of the principal techniques used for biomolecular analysis, with a focus on nucleic acids and proteins.
- Know how to interpret analytical data;
- Learn about the main applications in molecular diagnostics and chemical biology.
At the end of the course, the student is expected to:
- know the main biomolecular recognition processes underlying standard bioanalytical techniques and biosensors, including nucleic acid interactions, affinity binding processes and ligand-substrate interactions;
- have knowledge of the main biomolecular detection methods, including amplification techniques and immunoassays.
- be familiar with the main mass spectrometry-based instrumental techniques and the connected workflow used to analyze biomolecular species in complex samples.
- be able to read and process analytical data, also from a method validation perspective:
- recognize the potential, the limits and the drawbacks of the different techniques;
- develop critical thinking and creativity to address bioanalytical challenges
- build adequate communication skills and possess a good command of the terminology of the field.
- prove their ability to independently expand on the notions learned during the course, peruse the relevant literature and engage in the discussion of recent trends in bioanalytical chemistry.