Learning objectives
Students will acquire knowledges on microbial genomics applied to outbreak investigation, source attribution and risk assessment. Whole genome sequencing platforms and technologies will be described. Benefits of a real-time outbreak investigation and a more targeted source attribution and hazard identification/characterisation will be discussed along with major challenges and opportunities.
Prerequisites
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Course unit content
• Whole genome sequencing platforms and technologies
• Introduction to microbial risk analysis
• WGS and outbreak investigation (definition of outbreak, subtyping approaches, platforms for real-time outbreak investigation)
• WGS and source attribution (frequently matched, machine learning, network models)
• Genome Wide Association Studies and prediction of phenotypic traits
• WGS and risk assessment (pathogen typing and characterisation for hazard identification, prediction of virulence potential for hazard characterisation, prediction of phenotypic traits associated to growth/survival for exposure assessment)
Full programme
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Bibliography
Notes of lectures; scientific publications
Teaching methods
Oral lectures, scientific seminaries, laboratory activities
Teaching tools
projector, computer, instruments of microbiological laboratory
Assessment methods and criteria
This course is part of the integrated subject "RISK ANALYSIS IN THE FOOD CHAIN AND ANIMAL WELFARE” which also includes "RISK ANALYSIS IN ANIMAL WELFARE ". Final grading of the entire integrated course is calculated as an average of the scores obtained in the two courses of " RISK ANALYSIS IN ANIMAL WELFARE " and "MICROBIAL GENOMICS FOR RISK ANALYSIS". The examination commission includes teachers of both courses.
The oral examination will verify the theoretical and applicative knowledges of the student. Particularly positive will be evaluated the ability to move within the different topics and the achievement of an organic knowledge of the topics presented during the lessons
Other information
http://www.distal.unibo.it/
