Learning objectives
Considering the significant development and relevance of the structural biology, this course is designed to give students the bases to learn and understand the principles and practise of the most important methods to determine the structure, the conformational stability and dynamics of biomolecules in solution. Attending the course, that is based on theoretical lectures and laboratory practicals, will allow the students to verify their learning skills.
Prerequisites
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Course unit content
Forces that determine biomolecular structure. Structure and dynamics of proteins.
Basic principles of spectroscopy. Electromagnetic waves polarization. Interaction of radiation with matter.
Circular dichroism spectroscopy (CD): basic principles and application to the study of biomolecules.
Nuclear Magnetic Resonance (NMR) spectroscopy: basic principles and applications to the study of structure and dynamics of proteins in solution.
Methods to determine the three dimensional structure of proteins using NMR data.
Main features of Magnetic Resonance Imaging (MRI).
Fluorescence spectroscopy: basic principles and application to biochemical studies.
Laboratory practicals.
Full programme
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Bibliography
All the study materials are provided by the teacher.
Teaching methods
Frontal lectures and laboratory practicals.
Assessment methods and criteria
The exam consists of a written examination.
Other information
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2030 agenda goals for sustainable development
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