Learning objectives
Knowledge and understanding.
Students need learn the fundaments of the structure and component of the stem cell niches in different organs in the adult;
Applying knowledge and understanding
Students must use molecular and cellular techniques for development of a protocol for the isolation, characterization, expansion and differentiation of stem cells.
Making judgments
Ability to reason about molecular and cellular protocol for cell niche and stem cell study appeared on an article of an international journal and/or ph-thesis
Communications skills
Ability to understand and be understood in technical situations
Learning skills
Ability to summarize a technical procedure and to write a scientific progress report
Prerequisites
Human histology and anatomy.
Course unit content
Functional anatomy of the stem cell niche.
The hepatic stem cell niche,
The renal stem cell niche,
The neuronal stem cell niche,
The bronchioalveolar stem cell niche
The thymic stem cell niche,
The skeletal muscle stem cell niche,
Functional anatomy of the hemolymphopoietic organs
Full programme
Gain a detailed understanding on:
functional anatomy of the components that structure the stem cell niches in different organs in the adult;
structural and functional components of the niches of stem cells and of progenitors for the regeneration and repair of differentiated tissues; techniques of isolation, characterization, expansion and differentiation of hematopoietic, hepatic, renal, lung, skeletal muscle and neural progenitor cells;
biomechanics of structural, molecular and cellular bone and biomaterials in regenerative medicine
Program
Functional anatomy of the stem cell niche.
The hepatic stem cell niche,
The renal stem cell niche,
The neuronal stem cell niche,
The bronchioalveolar stem cell niche
The thymic stem cell niche,
The skeletal muscle stem cell niche,
Functional anatomy of the hemolymphopoietic organs
Bibliography
International reviews and scientific commentaries will dispensed by the teacher
Teaching methods
Oral lesson, lectures. Assimilation of scientific literature concerning the methods, the experimental protocols, the animal models, stem cell culture isolation and characterization procedures.
Assessment methods and criteria
End-of-term evaluation and continuous assessment. Written examination by a multiple (four) choice tests.
8 questions on the stem cell, the niche anatomy, the tissue regeneration. Students must answer correctly at least to 4 questions.
Other information
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