TECHNIQUES FOR BONE REGENERATION
cod. 1005381

Academic year 2014/15
2° year of course - Second semester
Professor
Carlo GALLI
Academic discipline
Medicina interna (MED/09)
Field
A scelta dello studente
Type of training activity
Student's choice
7 hours
of face-to-face activities
1 credits
hub: -
course unit
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Integrated course unit module: REGENERATION OF DIFFERENTIATED TISSUES

Learning objectives

The aim of the course is to provide student with operative knowledge of bone biology, focused on anabolic and catabolic processes, as they may be involved in designing novel approaches for bone regeneration

Prerequisites

Cell biology, histology

Course unit content

Analysis of cellular and molecular mechanisms underlying bone turnover and metabolism

Full programme

Basics of bone anatomy and histology
Osteoblasts, origin, differentiation and function
Osteoclasts, origin, differentiation and function
Osteocytes, morphology and physiology
Bone remodelling, and its regulation
PTH and PTHrP
Canonical wnt signaling and its function in bone
Mechanical loading and bone
Oxidative stress and bone

Bibliography

International reviews and scientific commentaries will provided by the teacher.
The following chapters will be useful for the course:
Strategies in regenerative medicine (Ed. M. Santin, Springer, 2009, pp. 55-154, 431-466);
Further reading:
Osteology guidelines for Oral and Maxillofacial Regeneration (Quintessence, 2011);
Fundamentals of Tissue Engineering and Regenerative Medicine (Springer, 2009)

Teaching methods

Lectures

Assessment methods and criteria

Written examination, multiple choice test

Other information

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2030 agenda goals for sustainable development

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