The aim of the course is to provide the students, by means of models peculiar of physical chemistry, with the thermodynamic concepts for knowledge and understanding of the energy interconversion in biological systems, the interaction of ligands with biological macromolecules and biological transport phenomena. Colloid chemistry, foundation of health products will be presented. The chemical-physical bases and methodologies for studying, designing and developing non-viral vectors will be presented., with particular emphasis on new cationic surfactants as possible mediators for gene delivery.
At the end of the course the student will have assimilated the main themes of Biologica Physical Chemistry demonstrating knowledge and understanding of the chemical-physical methods for the study of biological systems. The student will be able to identify and apply the appropriate model to each system and to calculate the thermodynamic parameters of the phenomenon observed.
At the end of the course, the student will have to demonstrate that he has assimilated the following topics:
- Principles of thermodynamics
- Relationships between thermodynamic quantities
- Chemical physical methods appropriate for the study of biopolymers
- Solution equilibria
- Membrane processes.
- Transport phenomena
- Colloidal systems
- non-viral vectors