REGENERATION OF DIFFERENTIATED TISSUES
cod. 1005434

Academic year 2012/13
2° year of course - Second semester
Professor responsible for the course unit
Prisco MIRANDOLA
integrated course unit
8 credits
hub:
course unit
in - - -

Learning objectives

Gain a detailed understanding on:
functional anatomy of the components that structure the stem cell niches in different organs in the adult;
structural and functional components of the niches of stem cells and of progenitors for the regeneration and repair of differentiated tissues;
techniques of isolation, characterization, expansion and differentiation of osteogenic, chondrogenic, hematopoietic, endocrine organs, skin and eye progenitor cells;
biomechanics of structural, molecular and cellular bone and biomaterials in regenerative medicine

Prerequisites

human anatomy and histolgy

Course unit content

Functional anatomy of the stem cell niche.
The corneal and retinal stem cells.
The epidermal stem cell
The hepatic stem cell niche,
The renal stem cell niche,
The neuronal stem cell niche,
The bronchioalveolar stem cell niche
The thymic stem cell niche,
The skeletal muscle stem cell niche,
Functional anatomy of the hemolymphopoietic organs
Regenerative medicine in endocrinology: biomaterials and the regeneration of endocrine and neuroendocrine tissues.
Ex situ bioengineering of endocrine and neuroendocrine organs
The skin regeneration techniques: immunobiology and skin regeneration.
Techniques of oral tissue regeneration
Biomaterials and implant prosthetics and tissue regeneration in periodontology
Techniques of bone regeneration
The biomechanic, structure, molecular and cellular properties of the bone
The osteogenic molecules in the regeneration and / or the ossteointegration between bones and stromal cells and biomaterials.
Regeneration techniques in eye diseases
New techniques in corneal transplantation.

Full programme

Functional anatomy of the stem cell niche.
The corneal and retinal stem cells.
The epidermal stem cell
The hepatic stem cell niche,
The renal stem cell niche,
The neuronal stem cell niche,
The bronchioalveolar stem cell niche
The thymic stem cell niche,
The skeletal muscle stem cell niche,
Functional anatomy of the hemolymphopoietic organs
Regenerative medicine in endocrinology: biomaterials and the regeneration of endocrine and neuroendocrine tissues.
Ex situ bioengineering of endocrine and neuroendocrine organs
The skin regeneration techniques: immunobiology and skin regeneration.
Techniques of oral tissue regeneration
Biomaterials and implant prosthetics and tissue regeneration in periodontology
Techniques of bone regeneration
The biomechanic, structure, molecular and cellular properties of the bone
The osteogenic molecules in the regeneration and / or the ossteointegration between bones and stromal cells and biomaterials.
Regeneration techniques in eye diseases
New techniques in corneal transplantation.

Bibliography

International reviews and scientific commentaries will dispensed by the teacher
issues.

Teaching methods

oral lessons

Assessment methods and criteria

written exam

Other information

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2030 agenda goals for sustainable development

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