Learning objectives
Learn the structure of DNA, the function of eukaryotic genes, the mechanisms of transmission and expression of genetic information, the mechanisms of DNA repair. Understand the basic techniques of recombinant DNA technology and cloning techniques.
Prerequisites
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Course unit content
Learn the structure of DNA, the function of eukaryotic genes, the mechanisms of transmission and expression of genetic information, the mechanisms of DNA repair. Understand the basic techniques of recombinant DNA technology and cloning techniques.
Full programme
Molecular basis of genetic information. Composition and structure of nucleic acids. Structure and function of eukaryotic gene. DNA replication. DNA repair mechanisms of gene expression in connection with human diseases, cell aging and cancer. Types of RNA: structure and functions. Genetic code and properties. Mechanisms of transcription. Protein synthesis. Regulation of gene expression and fate of post-synthetic proteins. Molecular biology techniques, cloning techniques, DNA sequencing, restriction enzymes and maps, transgenes and transgenic organisms, applications of biotechnology methods in forensic medicine.
Bibliography
Nelson DL, Cox MM: I principi di Biochimica di Lehninger, Zanichelli, Bologna.
Lewin, Krebs, Goldstein, Kilpatrick: Il gene. Zanichelli, Bologna.
Amaldi, Benedetti, Pesole, Plevani: Biologia Molecolare. Casa Editrice Ambrosiana, Milano.
Teaching methods
Oral lessons
Assessment methods and criteria
oral exam
Other information
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