Learning objectives
The program's goal is to give to the student the basic instruments to rationally understand the fundamental processes of the organic and applied Chemistry even in connection with the sustainable development.
Prerequisites
Exam of General and Inorganic Chemistry
Course unit content
The students will be first introduced to the basic theories of VSEPR and of the
valence bond for the description of organic molecules. Some basic concepts of
chemical thermodynamics and kinetics will be also reminded with particular
attention to 1st and 2nd order reactions, to chemical catalysis and to competitive
reactions. The concepts of nucleophile and electrophile will be compared with those
of Brønsted-Lowry and Lewis acid and base. The concepts of organic
stereochemistry will be described together with the stereochemical nomenclature
and properties of the stereoisomers with particular attention to biological and
pharmaceutical world.
A systematic survey of the structure, properties and reactivity of organic molecules,
divided by functional groups, will be undertaken. In particular this analysis will
include the following classes of organic compounds: Alkanes snd Cycloalkanes;
Alkenes and Alkynes; Alkyl halides; Alcohols, Ethers and Thiols; Benzenes and
Aromatic compounds; Amines; Ketones and Aldehydes; Carboxylic acids and their
derivatives.
Full programme
Summary of the fundamental physico-chemical notions about thermochemistry, thermodinamic and kinetic. Soft interactions. Covalent bond. Atomic electronic configuration. Lewis structure. Ionic bond. Electronic structure and molecular shape. sp3, sp2 and sp orbitals. Functional groups. Acids and bases. Bronsted-Lowry theory. Lewis theory. Acid-base equilibrium. Alkanes and cycloalkanes. Isomeric structures. Nomenclature. IUPAC system. Conformations. Physical properties. Reactions. Alkenes. Structure. cis-trans and E-Z systems. Preparation. Natural alkenes. Reactions. Alkynes. Structure. Nomenclature. Physical properties. Preparation. Reactions. Dienes. Structure. Electrophilic addition. 1,2- and 1,4- addition. Chyrality. Enantiomer classification. Fisher structure. Optical activity- R,S system. Enantiomers and diastereoisomers. Meso-compounds. Resolution. Alcohols. structure. Nomenclature. Physical properties. Preparation. Reactions. Alkyl halides. Structure. Nomenclature. Preparation. Reactions with acids and nucleophyles. Nucleophylic substitution. SN1 and SN2. Conversion of alcohols into alkyl halides. Substitution-Elimination reactions. Ethers and epoxides. Structure. Preparation. Reactions. Aromatic compounds. Structure. Aromaticity. Nomenclature. Electrophylic and nucleophylic aromatic substitution. Aromatics preparation. Aldehydes and ketones. Structure and nomenclature. preparation. Reactions. Carboxylic acids structure. Nomenclature. Acidity. Preparation. Reactions. Acid derivatives. Idrolysys and reactions in general. Enolate anions. Production. Aldol reactions. Malonic abd acetoacetic synthesis. Amines. Structure and classification. Basicity. Preparation and reactions.
Bibliography
W. H. Brown “Introduction to the Organic Chemistry” EDISES
Teaching methods
Oral lesson
Assessment methods and criteria
Oral examination
Other information
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2030 agenda goals for sustainable development
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