GENETICS
Course unit partition: Cognomi M-Z

Academic year 2009/10
1° year of course - Second semester
Professor
Francesco Maria RESTIVO
Academic discipline
Genetica (BIO/18)
Field
Ambito aggregato per crediti di sede
Type of training activity
Base
72 hours
of face-to-face activities
9 credits
hub: PARMA
course unit
in - - -

Course unit partition: GENETICS

Learning objectives

to provide the first year students with the basic concepts of classical genetics

Prerequisites

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Course unit content

 Characters segregation. Mendelian genetics. Independent assortment. Gene interaction. Chromosome theory of inheritance. Genes on X chromosome.  Chromosome structure in prokaryotes and eukaryotes. Multiple alleles. Linkage and recombination. Crossing over. Non-mendelian inheritance. Elements of microbial genetics. Recombination in yeast. Tetrad analysis. Recombination in bacteria, transformation, conjugation, recombination in virus. Identification of the genetic material. DNA: structure and replication. RNA structure, transcription and translation.  The one-gene:one-enzyme theory.   Structure of the gene (Benzer); complementation; cistron. Regulation of gene expression in prokaryotes. Operon Lac: negative and positive control. Spontaneous and induced mutation. Genome, chromosome and gene mutation.Setection of spontaneous or induced mutants. Selection strategy. Mutation frequency. Molecular basis of mutations. Physical and chemical mutagens. Reversion. Suppression. Population genetics.

Full programme

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Bibliography

<ul>
<li>Principi di Genetica , D.P. Snustad e M.J. Simmons ,terza edizione, EDISES</li>
<li>Genetica, B.A. Pierce , Zanichelli</li>
<li>Genetica Fondamenti, P.J. Russel, EDISES </li>
</ul>

Teaching methods

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Assessment methods and criteria

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Other information

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2030 agenda goals for sustainable development

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