Learning objectives
The course provides the information and the
scientific supports for
a correct methodological approach that develops the
knowledge and the
necessary understanding of the topics of Clinical
Biochemistry. This is to allow a
correct approach to the practical issues which are
specific to the student of the
Bachelor Degree in Techniques Of biomedical
laboratory. The acquired
skills will allow to understand the complexity of
biological samples, their
variability, and the critical steps associated with their
treatment and
conservation. This will allow you to recognize the
possible sources of
error and apply the appropriate remedies.
Prerequisites
There is no mandatory propedeuticity, but
considering that Clinical
Biochemistry is an interdisciplinary subject, the
student should have the
basic concepts of Biology, Anatomy,
Chemistry and
Biochemistry.
Course unit content
The course integrates , Physiology, Biochemistry,
Instrumental Biochemistry and Clinical
Biochemistry.
Full programme
The use of laboratory data in clinical practice. The
interpretation of
biochemical data. Reference and variability of
laboratory data. Disorders
of the hydrosiline equilibrium and of the acid-base
balance. Mechanisms underlying the general
functions of the cells as transports, electrical and
chemical communication, mechanical activity,
metabolism.
Functions of the main apparatus of the body as
cardiovascular, pulmonary, renal and endocrine.
Isoenzymes.
Determination of enzymatic activity. Analysis of
blood and urine.
Evaluation of hepatic function and diagnosis of
jaundice. Diabetes mellitus.
Glycemic homeostasis. Nucleotide metabolism and
hyperuricemia.
Metabolism of amino acids in clinical biochemistry.
Clinical Molecular
Biology and Molecular Diagnosis. Tumor markers.
Bibliography
FISIOLOGIA, dalle molecole ai sistemi integrati. E.
Carbone, F. Cicirata, G. Aicardi. Ed. EdiSES
CLINICAL BIOCHEMISTRY
Biochimica clinica essenziale- dal laboratorio ai
quadri di patologia clinica. Elisabetta Albi, Zanichelli
editore
Biochimica clinica e medicina di laboratorio,
Marcello Ciaccio e Giuseppe Lippi, Edises
Principi di biochimica Lehninger - Zanichelli Editore
L. Spandrio “Principi e tecniche di chimica clinica”
Piccin Editore
Widmann “Interpretazione clinica degli esami di
laboratorio” edizione italiana a cura di G. Gazzola,
R. Franchi-Gazzola, V. Dall’Asta, O. Bussolati, R.
Sala R. Malvano, A. Chiacchio, G. Vignati “Il valore
diagnostico del dato di laboratorio” G. Polizzi, C.
Gagliano “La variabilità preanalitica”
Teaching methods
Lectures will be held on-site in compliance with
safety standards, provided that further instructions
on the ongoing health emergency are not
implemented. Supporting material will be available
on the specific, student-reserved platform (Elly) and
will include slide presentations, audio-video aids or
video-recording of the lectures.
Assessment methods and criteria
The final exam is oral and focuses on the topics of the program.
Other information
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