Learning objectives
This core module aims to provide students with an understanding of mesenchymal cell characteristics and their potential in regenarative medicine. Peculiar attention will be paid on molecular characterization and on molecular mechanism of cell differentiation.
Prerequisites
None
Course unit content
The subjects presented in the lectures will be: cord blood, Wharton's jelly and placenta as sources of stem cells; mesenchymal cells from adult tissues; gene expression profile of mesenchymal cells and methods for molecular characterization; culture and expansion of mesenchymal cells in vitro; functional characteristics of mesenchymal cells: homing and trafficking.
Full programme
- Adult tissues and embryonic annexes as sources of mesenchymal stem cells
* Gene expression profile of mesenchymal cells and methods of molecular characterization
- Cultivation and in vitro expansion of mesenchymal cells
- Functional characteristics of mesenchymal cells: trafficking and homing
- Applied Engineering in mesenchymal cells
- Possible application of mesenchymal cells: the regeneration of beta cells
Bibliography
Mesenchymal Stem Cells - Methods and Protocols (Methods in molecular biology 449)
Editors: Darwin J. Prockop , Donald G. Phinney ,Bruce A. Bunnell
ISBN: 978-1-58829-771-6 e-ISBN: 978-1-60327-169-1 DOI: 10.1007/978-1-60327-169-1 © 2008 Humana Press,
CULTURE OF HUMAN STEM CELLS
Editors: R. IAN FRESHNEY, GLYN N. STACEY, JONATHAN M. AUERBACH, WILEY-INTERSCIENCE. ISBN 978-0-470-05246-4
Teaching methods
Visual tutorials will support oral lessons. This material will be availble to students at the end of the course.
Assessment methods and criteria
Oral exam
Other information
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2030 agenda goals for sustainable development
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