Learning objectives
This course aims to provide the informations and the scientific underground to approach correctly the methodology in Clinical Biochemistry. The purpose is a correct use and development of diagnostic products for Clinic\al Biochemistry and of devices for the collection, treatment and storage of biological samples.
Prerequisites
Besides the obligatory prerequisites, it is appropriate that the student is able to manage the basic concepts of Chemistry, Biochemistry and Physiology.
Course unit content
The biological sample: characteristics, instruction for optimal collection, treatment and conservation (avoiding pre-analytical variation).
The main analytical techniques and instrumentations to evaluate the molecules of interest in Clinical Chemistry. Analytical and post-analytical variability affecting the laboratory data. Clinical laboratory quality assurance.
Current waived laboratory test. Criteria for test waiving. Kits for diagnostic tests. Evolution Point of care testing (POCT) technology. Quality control in POCT.
Principles to detect the markers of organ function and lesion; analytical procedures and clinical correlations.
Methodology of therapeutic drug monitoring, detection of toxic compounds, abuse substances and of sport doping.
Full programme
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Bibliography
R.A. Sacher, R.A. McPherson Interpretazione clinica degli esami di laboratorio Ed. McGraw-Hill, New York
Teaching methods
The final oral examination is about the topics of the course; the student needs to demonstrate to have understood and to be able to manage the essential meanings of every section of the program.
Assessment methods and criteria
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Other information
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2030 agenda goals for sustainable development
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