MEDICAL, VETERINARY ANF PHARMACEUTICAL BIOTECHNOLOGIES

Professor: Stefano GROLLI
Academic discipline: Biochimica (BIO/10)
Field: A scelta dello studente
Type of training activity: Student's choice

28 hours
of face-to-face activities

4 credits

hub: -

course unit
in - - -

lectures timetable unavailable

exam calls

Integrated course unit module: ORIGIN, DIFFERENTIATION AND HANDLING OF STEM CELLS

Learning objectives

The main objectives of the course are the understanding of the technologies employed for the manipulation of the genome and the production and manipulation of stem cells.

Prerequisites

Course unit content

The course will describe the main techniques use for the manipulation of the genome and the applications of these technologies in both the biomedical and veterinary fields will be described, together with the problems arising from theit use.

Full programme

The course will describe the fundamental aspects of:

- Farm animal transgenesis and cloning: biological background, history, techniques.

- Biomedical applications: animal as bioreactors; animal as models of human and mammalian diseases; genetically modified animals and xenotrasplantation.

- Zootechnical application of genome transgenesis and cloning: animal growth modification; milk and body composition modification; disease resistance modification; reproductive performances modification.

- Social and economic implications of genome manipulation: animal welfare; food safety issues related to genetically modified foods; functional foods.

- Stem cell biology. Mesenchymal stem cells, induced pluripotent stem cells: biology and clinical applications. Perspectives and limits.

Bibliography

The students will be given articles and the slides used by the teachers.

Teaching methods

Before each new lesson, the teacher will first summarise then check whether the previous topics have been well understood through an interactive discussion with the students.

Assessment methods and criteria

At the end of the course, the students must be capable of discussing critically and with the appropriate language on the molecular bases of mammalian reproduction, preimplantation development and on the biology of the embryonic stem cells. Also, they will have understood how the manipulation of the genome and the use of stem cells may impact on both fields of medicine and animal production. The students will have to be able to discuss the advantages, but also the limits of the technologies, including the ethycal and the animal well-being issues. Furthermore, the students must be capable of making links between these knowledges and those complementary of the veterinarian.

Other information

- - -

2030 agenda goals for sustainable development

- - -

Contacts

Toll-free number

800 904 084

Segreteria studenti

E. [segreteria.medicina@unipr.it]
T. +39 0521 903700

Servizio per la qualità della didattica

Manager della didattica:
Rag. Sabrina Ferrari
T. +39 0521 903109
E. servizio [didattica.dimec @unipr.it]

Presidente del corso di studio

Prof, Nicola Giuliani
E. nicola.giuliani@unipr.it

Delegato orientamento in uscita

Prof.ssa Sara Nicoli
E.sara.nicoli@unipr.it

Delegati Erasmus

Prof. Roberto Sala

E. roberto.sala@unipr.it

Referente assicurazione qualità

Prof.ssa Carlotta Compari
E. carlotta.compari@unipr.it

Tirocini formativi

Prof.ssa Laura Giovati

E. laura.giovati@unipr.it

HANDLING OF ANIMAL GENOME: TRANSGENIA, CLONING cod. 1005384