Learning objectives
To teach to the students the scientific methodology of Organic Chemistry<br />To provide the students with the bases to understand and explain the reaction mechanisms of the different mono and poli functional groups subjects of the course<br />To provide the students with the bases for the study of the structure and reactivity of the main classes of biomolecules<br />To show to students how a molecularly based approach can rationalise other related sectors such as Biology an Biotechnology;
Prerequisites
To get through the examination of Organic Chemistry and Laboratory of Organic Chemistry I°
Course unit content
Module 1: Heteroaromaticity: aromaticity and antiaromaticity; five membered ring and six membered ring heterocicles; reactivity, electrophilic aromatic substitution; fused rings<br />Module 2: Synthetic polimers: omopolimers and copolimers; condensation polimers and addition polimers; mechanisms of polimerisation; stereospecific polimers; biocompatible and biodegradable polimers<br />Module 3: Carbonyl compounds: nucleophilic addition; hydratation, reaction with alcohols, reaction with amines, reactions with carbon nucleophiles, Wittig reaction; nucleophilic addition to alfa-beta unsaturated carbonyl componds<br />Module 4: Carboxylic acids and derivatives: acidity; nucleophilic acylic substitution; carboxylic acid derivatives; electrophilic rearrangements; thioesters and mixed anhydrides; <br />Module 5: Reactions at the alfa carbon: keto-enol tautomerism; alfa alogenations; malonic and acetoacetic synthesis; aldolic condensation; Claisen condensation; Michael reaction; <br />Module 6: Amines: basicity; synthesis and reactivity; ammonium quaternary salts<br />Module 7: Carbohydrates: monosaccharides, disaccharides, polisaccharides; furanosic and pyranosic structures; stereochemistry, anomers, epimers; glicosidic bond; cellulose, amylose, glycogen<br />Module 8: Amino acids, peptides, proteins: structures, isoelectric points, reactivity; peptides, structure and synthesis;proteins, structure and function<br />Module 9: Lipids: triacylglycerols, waxes, steroids, terpenes<br />Module 10: Nucleic acids: mononucleosides and mononucleotides; purinic and pyrimidinic bases; DNA, RNA
Bibliography
J. McMurry, Organic Chemistry, Piccin Padova<br />- Brown and Foote, Organic Chemistry, Edises Napoli<br />- P. Vollhardt and N. Schore, Organic Chemistry, Zanichelli Bologna
Teaching methods
Frontal lectures and exercises
Assessment methods and criteria
Written examination and oral examination at the end of the course.
