Learning objectives
The target of the course is to allow the student to know and to understand the essential elements of the tissues and organs structure. The student will utilize knowledge and understanding for Anatomy and Physiology future study.
1 Dublin descriptor - knowledge and understanding: the student must be able to systematically and topographically describe the conformation and structure of tissues in the ultrastructural aspects of cell morphology and describe the organogenesis and the stages of development.
2 Dublin descriptor- applied knowledge and understanding: identify morphological and functional diversity, provide a methodological approach preparatory to clinical reasoning.
3 Dublin descriptor - making judgements: the student must be able to sustain a functional histological/morphological reasoning.
4 Dublin Descriptor - Communication skills: The student must possess a precise technical language in histology and microscopic anatomy.
5 Dublin descriptor - learning skills: the student must be able to synthesize autonomously the numerous histological and morphological information in a functional perspective
At the end of the course the student will demonstrate knowledge and understanding about: Cell structute and organization, Tissue structure and organization, Multi tissutal units structure and organization. Moreover at the end of the course, students will be aquire knowledge and understanding applying knowledge or learning skills to discuss critically the molecular bases of cell structure and tissue organization
Prerequisites
- - -
Course unit content
Nella prima parte corso di istologia corso verranno sviluppati gli aspetti strutturali e funzionali della materia vivente e delle sue modalità di aggregazione a formare le cellule. Successivamente verranno illustrati gli aspetti strutturali e funzionali delle differenti cellule. Nella seconda parte del corso verranno analizzate le modalità di sviluppo delle cellule, fino ad arrivare allo sviluppo dell’intero embrione e degli annessi embrionali. Nella terza parte del corso verranno analizzati gli aspetti strutturali e funzionali dei tessuti e le loro modalità di aggregazione nel formare unità pluritissutali e organi.
Full programme
The cell. Chemical and physical aspects. biological properties
The extracellular matrix. Chemical and physical aspects. Biological properties. Morpho-functional
The cell as a thermodynamic system. The cell system as planned. The cell as a chemical environment. The cell as a physical environment. The animal cell
The supracellular units. The fabrics. Organs. The apparatus and systems
Fundamentals of technology. Analytical methods and biochemical methods histochemical investigation. Microscopy investigation of the morphology. The microscopes. Utility and technical limitations of the various microscopes. The histological stable. Preparation of histological stable
Principles of reading a histological preparation
The biomolecules. Morpho-functional aspects and location, humans, water, minerals, carbohydrates, lipids, proteins and nucleic acids
The supramolecular complexes. Stable supramolecular complexes. Labile supramolecular complexes.
The organs and systems of the cell. The cytoplasmic matrix. The cell periphery. The nucleus. Ribosomal subunits, ribosomes, polysomes and endoplasmic reticulum. The Golgi complex. The complexes endosomal. The vesicles and vacuoles. The peroxisomes. The mitochondria. Centrosome, mitotic spindle and asters
The cell cycle. The mitotic cell cycle. The meiotic cell cycle. Cell cycle kinetics
Cell senescence. The cell death
Somatic cells and germ cells
Stem cells and differentiated cells. The cell populations.
Embryonic development. The stages of development. Differentiation and growth
Morphological aspects of development. The week of development. II week of development. III week of development. IV week of development. II-III months of development. II-III trimester of development. Genetics of morphogenesis.
Development of the main systems and organs. Biological aspects of development. The factors of development. The microenvironment. Induction. Determination. Differentiation
The ultimate fabrics. Epithelial tissues. Tropho-mechanical tissues. Muscle tissues. Nerve tissues
Adnexal tissues. The tissues of the placenta. The tissues of the amniotic sac. The tissues of the yolk sac. The tissues of the umbilical cord. Histophysiology of embryo-fetal appendages
Multi-tissue units. The endocrine and exocrine glands. The mucous membranes of the alimentary canal, of the apparatus. respiratory, urinary tract, genital system. and the male genital system. Serous membranes. The skin. Skin productions.
Blood vessels and lymphatic vessels. Muscles. Nervous tissue. The bones. Nerves. The ganglia.
Bibliography
Principali testi di riferimento:
-M. Mattioli Belmonte et al. ISTOLOGIA UMANA; Casa Editrice Idelson-Gnocchi, ed. 2021
-NM Maraldi et al. ISTOLOGIA MEDICA; Casa Editrice Edi Ermes ed. 2016
-NM Maraldi et al. BIOLOGIA-CITOLOGIA MEDICA; Casa Editrice Edi Ermes ed. 2016
-A.L. Kierszenbaum, L.L. Tres ISTOLOGIA Dalle basi molecolari alle correlazioni cliniche; Casa Editrice EDRA, ed. 2020
-G. Bertini et al. EMBRIOLOGIA UMANA; Casa Editrice Idelson-Gnocchi, ed. 2019 The main books adopted are:
-M. Mattioli Belmonte et al. ISTOLOGIA UMANA; Casa Editrice Idelson-Gnocchi, ed. 2021
-NM Maraldi et al. ISTOLOGIA MEDICA; Casa Editrice Edi Ermes ed. 2016
-NM Maraldi et al. BIOLOGIA-CITOLOGIA MEDICA; Casa Editrice Edi Ermes ed. 2016
A.L. Kierszenbaum, L.L. Tres ISTOLOGIA Dalle basi molecolari alle correlazioni cliniche; Casa Editrice EDRA, ed. 2020
-G. Bertini et al. EMBRIOLOGIA UMANA; Casa Editrice Idelson-Gnocchi, ed. 2019
Teaching methods
The course will be held through lectures to Students in the classroom (“in presenza”) or in synchronous-streaming (“in telepresenza”) on the Teams platform in case of the persistence of the health emergency. Therefore, the opportunity of Student/Teacher interaction will be preserved both face to face and remotely, by the simultaneous use of the Teams platform.
Lectures will be supported by slide presentations, which will be available to students on the Elly platform (https://elly2020.medicina.unipr.it/).
Assessment methods and criteria
Oral examination.
In case of the persistence of the health emergency, the exams will be conducted remotely, as follows:
remote oral questions, through the Teams platform (guide http://selma.unipr.it/).
Students with SLD / BSE must first contact Centro per accoglienza e inclusione CAI supporting students with disabilities,SLD, BES. (https://www.cai.unipr.it/)
Other information
- - -
2030 agenda goals for sustainable development
This teaching contributes to the realization of the UN objectives of the 2030 Agenda for Sustainable Development
