LABORATORY OF ORGANIC CHEMISTRY I
cod. 1006236

Academic year 2022/23
1° year of course - Second semester
Professor
MAESTRI Giovanni, VOLPI STEFANO, CERA GIANPIERO
Academic discipline
Chimica organica (CHIM/06)
Field
Discipline chimiche
Type of training activity
Basic
62 hours
of face-to-face activities
6 credits
hub: PARMA
course unit
in ITALIAN

Learning objectives

Knowledge and understanding: the course will provide the students with
the theoretical and practical knowledge of the main experimental
techniques of the organic chemistry laboratory. Special emphasis will be
given to safety related issues. Moreover, the course content
complements the theoretical concepts acquired in the Organic Chemistry
I course.
Learning skills: the students will master a formally corrected scientific
language. They will also be able to clearly express organic chemistryrelated
concepts and to write a scientific report.
Applying knowledge and understanding: at the end of the course, the
students will be able to independently carry out the purification and
characterization of an organic compound working in safe conditions.

Prerequisites

Knowledge of the contents of the General and Inorganic Chemistry course

Course unit content

Introduction to the organic chemistry laboratory.
Introduction to IR and UV-Vis spectroscopic techniques.
The most important separation techniques in the organic chemistry
laboratory: theory and practice.
Theoretical and practical approach to an organic synthesis reaction

Full programme

Introduction to the organic chemistry laboratory: safety regulations;
laboratory equipment: risks and use; use of laboratory solvents.
DI: Knowledge and understanding; applying knowledge and understanding

Introduction to IR and UV-Vis spectroscopic techniques: basic concepts connected with bonding theory; links between polarity/polarizability of bonds and the structure of organic molecules; consequences on their physico/chemical properties and reactivity.
DI: Knowledge and understanding.

Examples of structural determination and identification of functional groups by IR & UV-vis spectroscopies.
DI: making judgements; applying knowledge and understanding

Laboratory separation techniques: purification of solids and purity
criteria; the choice of the solvent and melting point determination;
extraction techniques of organic compounds; natural product extraction;
basic and acid substances extraction; chromatographic separations; the
choice of the eluent, thin layer chromatography, column
chromatography, gaschromatography; distillation techniques: simple
distillation and fractional distillation.
How to run an organic synthesis reaction.
DI: Knowledge and understanding; applying knowledge and understanding

Laboratory experiences:
Purification of an organic compound through recrystallisation;
Separation of organic products through acid-base extraction;
Caffeine extraction from tea leaves;
Thin layer chromatography and column chromatography;
Electrophilic aromatic substitution reactions; through all of these examples, it will be showed, and then checked all along, the series of skills and knowledges required to plan, get additional info whether necessary, execute and analyze a scientific experiment, together with drafting/discussing data, and the safe disposal of all wastes.

DI: making judgements; applying knowledge and understanding

Final test.
DI: - Applying knowledge and understanding;
- Making judgements;
- Communication skills;

Bibliography

M. D’Ischia, “La Chimica Organica in Laboratorio” (2 volumes), Piccin.
R.M. Silverstein, F.X. Webster, “Identificazione Spettroscopica di
Composti Organici”, Ed. Ambrosiana.

Teaching methods

The course will be held through 32 hours of lectures and 30 hours of
laboratory experiences. Whether external circumstances will be forcing, the whole program or part of it might be discussed remotely. Close to the beginning of the term, the didactic repository will be updated to inform students on the organization of teaching.

Assessment methods and criteria

Answers to each pre-lab set of problems and the correct/safe execution of each practical experiment will be verified; similarly, the quality of the lab journal will be evaluated. The practical laboratory exam will verify the ability to plan and
independently carry out simple laboratory operations involving organic
compounds working under safe conditions. The oral exam will test the knowledge of the theory related to the
laboratory experiences, the ability to explain the IR or UV-Vis spectra of simple
organic compounds and the ability to solve exercises related to acid/base equilibria and electrophilic aromatic substitutions.
DI: Making judgements; Knowledge and understanding; applying knowledge and understanding; Communication skills.

Other information

Lecture notes are available on the web.
The teacher is available upon request for discussion and explanation of
specific topics.
Information on the content of the course (see below) are associated with the relative "Dublin Indicators" (DI) that characterize their purposes.
Dublin Indicators:
- Knowledge and understanding;
- Applying knowledge and understanding;
- Making judgements;
- Communication skills;
- Learning skills.