Learning objectives
The program's goal is to give to the student the basic instruments to
rationally
understand some of the fundamental processes of the organic and applied
chemistry.
Prerequisites
Good knowledge of the fundamental principles of the general chemistry, in particular of the atomic structure, of the chemical bond and of the chemical equilibrium; in addition the student must have a good knowledge of the acid/base concepts.
Course unit content
The students will be first introduced to the basic theories of VSEPR and of the valence bond for the description of organic molecules. Some basic concepts of chemical thermodynamics and kinetics will be also reminded with particular attention to 1st and 2nd order reactions, to chemical catalysis and to competitive reactions. The concepts of nucleophile and electrophile, those of Brønsted-Lowry and Lewis acid and base will be considered. The concepts of organic stereochemistry will be described together with the stereochemical nomenclature and properties of the stereoisomers. A systematic survey of the structure, properties and reactivity of organic molecules, divided by functional groups, will be undertaken. In particular this analysis will include the following classes of organic compounds: alkanes and cycloalkanes; alkenes, dyenes and alkynes; alkyl halides; alcohols, ethers and thiols; benzenes and aromatic compounds; amines.
Full programme
INTRODUCTION: Summary of the fundamental physico-chemical notions about thermochemistry, thermodynamic and kinetic. Soft interactions.
COVALENT BOND: atom electronic configuration; Lewis structures; ionic bond; electronic structure and molecular shape; sp3, sp2 and sp orbitals;
functional groups. DI: Knowledge and understanding.
ACIDS AND BASES: Arrhenius and Bronsted-Lowry theoroies; Lewis theory; acid-base equilibrium. DI: Knowledge and understanding.
ALKANES AND CYCLOALKANES: structure, isomers; nomenclature; IUPAC system; conformations; physical properties; reactions. DI: Knowledge and
understanding.
CHIRALITY: enantiomer classification; Fisher structure; optical activity; R,S system; enantiomers and diastereoisomers; mesocompounds; resolution. DI: Knowledge and understanding.
ALKENES: structure; nomenclature; cis-trans and E-Z systems; preparation; natural alkenes; reactions. DI: Knowledge and understanding.
ALKYNES: structure; nomenclature; physical properties; preparation; reactions. DI: Knowledge and understanding.
CONJUGATED DIENES: structure, nomenclature; 1,2- and 1,4-electrophylic additions. DI: Knowledge and understanding.
ALKYL HALIDES: structure; nomenclature; preparation; nucleophilic substitution: SN1 and SN2; conversion of alcohols into alkyl halides; substitution vs elimination reactions. DI: Knowledge and understanding; making judgements.
ALCOHOLS: structure; nomenclature; physical properties; preparation; reactions. DI: Knowledge and understanding; making judgements.
ETHERS AND EPOXIDES: structure; preparation; reactions. DI: Knowledge and understanding; making judgements.
AROMATIC COMPOUNDS: structure; aromaticity; nomenclature; electrophilic aromatic substitution. DI: Knowledge and understanding; making judgements; applying knowledge and understanding.
AMINES: structure and classification; basicity; preparation and reactions. DI: Knowledge and understanding; making judgements; applying
knowledge and understanding.
Bibliography
The slides utilized during the whole course are available to the tudents on the web site of the Course.
W. H. Brown, C. S. Foote, “Chimica organica” - EDISES
Teaching methods
Oral lessons and weekly exercises. The lessons will be organized in presence with the possibility to have lessons also remotely in asynchronous mode (uploaded on the Elly page of the course)
Assessment methods and criteria
1) IT IS POSSIBLE TO CONDUCT EXAMINATIONS IN PRESENCE.
In this case the examination will consist in a written test (2 hours) followed by and oral discussion aimed to verify the ability of the student to face organic reaction problems. The exam is passed with a score of at least 18.
2) IT IS NOT POSSIBLE TO CARRY ON EXAMINATION IN PRESENCE (ONLY ON-LINE).
In this case, the evaluation will consist in a written test (1 hour and 20 minutes) followed by and oral discussion aimed to verify the ability of the student as described above.
Other information
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