BASES OF IMMUNE RESPONSE
cod. 1005417

Learning objectives

The course aims to provide students with the essential bases of both innate and specific immune response. Such knowledge will help the student in the understanding of certain diseases in dentistry.

Prerequisites

Course unit content

The course will concern on the following content:
Nomenclature and components of the immune system.
General characteristics of immune responses.
Mechanisms of innate immunity and adaptive immunity.
Autoimmunity and immunodeficiency,
Reactions of hypersensitivity.

Full programme

Innate immunity: Phagocitosis; Complement activation.
Specific Immunity: Cell-mediated Immunity. Antigen recognition and effector functions of T lymphocytes. The Major Histocompatibility Complex.
Humoral Immunity. Immunoglobulin types. Antigen recognition and effector functions of immunoglobulins. The memory of immune system.
Immunological tolerance. Loss of tolerance and autoimmunity. Immunodeficiencies.
Hypersensitivity reactions (I-IV), with clinical examples (allergic reactions; transplant rejection).

Bibliography

Abbas-Lichtman-Pober "Immunologia cellulare e molecolare" Ed. PICCIN
Mak-Saunder "Fondamenti di Immunologia" Ed. ZANICHELLI

Teaching methods

During the lectures will be explained the bases of immune response, with the help of slides prepared by the teacher,. The slides will be available for the students on Elly site (https://elly2020.medicina.unipr.it/), at the page of the course. The lectures will be open to wide-ranging discussion with the participation of the students. The course will be held either in the classroom (“in presenza”) or in synchronous-streaming (“in telepresenza”) on the Teams platform (for instructions, see http://selma.unipr.it); therefore, the opportunity of Student/Teacher interaction will be preserved both face to face and remotely, by the simultaneous use of the Teams platform.

Assessment methods and criteria

The degree of learning will be assessed at the end of the course through oral examination to establish the learning outcomes on the bases of the proposed objectives. In particular, the student will be able to know the essential bases of immune response and to understand the mechanisms that regulate this response. The student will be evaluated with votes ranging from 0 to 30, with 18 being the lowest vote to positively pass the exam. The final vote will be decided by mutual agreement among the teachers of the integrated course. In case of the persistence of the health emergency, the exams will be conducted remotely, as follows: remote oral questions, through the Teams platform (guide http://selma.unipr.it/).
Students with SLD / BSE must first contact Le Eli-che: support for students with disabilities, D.S.A., B.E.S. (https://sea.unipr.it/it/servizi/le-eli-che-supporto-studenti-con-disabilita-dsa-bes)

Other information

2030 agenda goals for sustainable development