CLINICAL PATHOLOGY
cod. 06175

Academic year 2021/22
3° year of course - Second semester
Professor
- Amelia BARILLI
Academic discipline
Patologia clinica (MED/05)
Field
Discipline mediche di rilevanza odontoiatrica
Type of training activity
Characterising
40 hours
of face-to-face activities
4 credits
hub: PARMA
course unit
in ITALIAN

Integrated course unit module: MEDICAL SCIENCES I

Learning objectives

The Course of Clinical Pathology is part of the Integrated Course of Medical Sciences1.

The course aims to enable the student to know and understand the main laboratory tests, in order to achieve the ability to use the knowledge and understanding gained in identifying the patient's problems related to the disease.

Prerequisites

Basic knowledge of biology, cytology, histology and genetics is required to understand the topics covered in the course

Course unit content

The course will concern on the following content:
1.Generalia of clinical patholgy
2. Blood and cytometric exams
3.The laboratory in the diagnostic of anemias
4. Serum proteins
5.The laboratory in the evaluation of hemostatic function
6. Transfusion medicine
7. First level laboratory tests for the study of liver function
8. Laboratory tests for the study of kidney function
9.The laboratory in diabetes mellitus
10.The laboratory in cardiovascular diseases
11.The laboratory in respiratory diseases
12. Analysis of the cephalo-rachid fluid
13.Tumor markers

Full programme

Insertion of the Laboratory data in the diagnostic procedure and its functions in other optics such as prevention, prognosis, therapy and screening. Emergency exams and routines (examples)
Evaluation criteria of the analytical data
Factors that influence the reliability and interpretation of laboratory data:
Preanalytic variability
Analytical variability

Hematopoietic system
Hemochromocytometric examination

Evaluation of iron metabolism
Hemoglobin and Bilirubin
Laboratory diagnostics anemias and diseases white blood cells

Plasma proteins
Electrophoresis
Albumin and globulins
Meaning specific protein dosage
Dosage of plasma enzymes and hormones

Haemostasis
Evaluation of coagulation, fibrinolysis, platelet function
Major laboratory diagnostics coagulopathies

Hepatic system
Main hepatic enzymes
Bile and bilirubin
Jaundice and urea cycle

Renal system
Chemical-physical examination of urine
Osmolarity and specific weight
Dosing of the main electrolytes
Uriemia, azotemia, creatinine (and clearance)
Proteinuria, glycosuria, hemoglobinuria, hematuria

Endocrine system
Diabetes laboratory diagnostics

Cardiovascular system
Cardiac ischemia markers

Respiratory System
emogasanalisi

Analysis of the cephalo-rachid fluid
The cerebro-spinal fluid
Liquor evaluation

Tumor markers

Bibliography

G. Federici: Medicina di laboratorio – McGraw – Hill (last edition)

Widmann: Interpretazione clinica degli esami di laboratorio – McGraw – Hill (ultima edizione)

M. Ciaccio, G. Lippi: Biochimica Clinica e Medicina di Laboratorio - EdiSes (ultima edizione)
The slides used during the lectures will be made available on the Elly Platform.

Teaching methods

The course will be conducted through interactive lectures in front of the students, with the aid of illustrative material that, at the end of the course, will be made available to students on Elly site (https://elly2020.medicina.unipr.it/) at the pages of the course.
Lectures will be held on-site in compliance with safety standards, provided that further instructions on the ongoing health emergency are not implemented.
During the lessons we will discuss the issues related to laboratory tests and their interpretation topic will be exposed, encouraging students to ask questions on the basis of references that will be provided.

Assessment methods and criteria

Verification tests in progress will not be carried out. Final assessment will be carried out through oral examination, aiming to evaluate the communication and learning skills of the student, as well as his/her ability to judge the health status of the hypothetical patients.
In case of the persistence of the health emergency, the exams will be conducted remotely, as follows: remote oral questions, through the Teams platform (guide http://selma.unipr.it/).
Students with SLD / BSE must first contact Le Eli-che: support for students with disabilities, D.S.A., B.E.S. (https://sea.unipr.it/it/servizi/le-eli-che-supporto-studenti-con-disabilita-dsa-bes).
Each student will be asked questions on topics listed in the extended program. The inability to answer a question (or at least ascertained inability to provide a correct definition of the pathological phenomenon subject of the application) will result in not passing the exam.
The student will be evaluated with votes ranging from 0 to 30, with 18 being the lowest vote to positively pass the exam. The final vote will be decided by mutual agreement among the teachers of the integrated course.

Other information