Learning objectives
As part of the integrated course, the course aims to provide the knowledge necessary for the understanding of disease processes from a molecular and cellular point of view. The knowledge gained will enable students to correlate molecular alterations with microscopic and macroscopic alterations observable in cells, tissues and organs, in order to fully understand the pathogenesis of the disease. Bibliographical references may be used to acquire independent judgment, communication skills and learning ability, which can be demonstrated during the examination.
Prerequisites
It is advised to have supported the examinations of the previous year
Course unit content
The course will concern on the following content:
- Inflammation
- Immunity
- Neoplasms
- Diabetes
- Haemostasis and its alterations
Full programme
Damage and cell death
Inflammation
Signs and phenomena of the acute inflammation
Inflammatory exudates
Phagocytoses
Chemical inflammatory mediators
Chronic inflammation
Atherosclerosis
Neoplasia
Nomenclature
Epidemiologia
Differences between benign and malignant tumors
Molecular bases of the neoplasie
Metastasis
Haemostasis and its alteration
Thrombosis and ischemia
Defects in hemostasis
Immunity
Innate and acquired immunity
Diabetes
Mutations and inheritance
Mitochondrial diseases
Bibliography
One text chosen between the following:
- 1. Spector e Axford, Introduzione alla Patologia Generale, CEA
- 2. Woolf, Patologia Generale – Meccanismi della malattia, Idelson-Gnocchi
- 3. Caruso e Licastro – Compendio di Patologia Generale. Casa Ed. ambrosiana
- 4. Pontieri, Patologia e fisiopatologia generale Ed. Piccin
Teaching methods
The course will be conducted through interactive lectures in front of the students, with the aid of illustrative material collected in PowerPoint files that, at the end of the course, will be made available to students.
During the lectures the main concepts of each topic will be exposed, encouraging students to ask questions on the basis of references that will be provided.
Assessment methods and criteria
Verification tests in progress will not be carried out.
Final assessment will be carried out through oral examination.
Each student will be asked two questions on topics listed in the extended program. The inability to answer a question (or at least ascertained inability to provide a correct definition of the pathological phenomenon subject of the application) will result in not passing the exam.
At the end of the answer the teacher will formulate a judgment given in brackets:
A. Excellent knowledge and understanding of the topic. High capacity for applying knowledge in bio-medical problems. Vote of thirty: 30.
B. Good knowledge and understanding of the topic. Good ability to apply knowledge in bio-medical problems. Vote of thirty: 27-29.
C. Good knowledge and understanding of the topic. Demonstrated ability to apply the knowledge in bio-medical problems. Vote of thirty: 24-26.
D. Knowledge and understanding of the fully sufficient. Fair ability to apply the knowledge in bio-medical problems. Vote of thirty: 21-23.
E. Knowledge and understanding of the subject just enough with obvious gaps. Poor ability to apply knowledge in bio-medical problems. Vote of thirty: 18-20.
Laud will be proposed for the demonstration of independence of judgment, high communication skills and ability to learn independently.
The vote will be decided by mutual agreement between the two teachers, with the possibility to deviate by a maximum of two points of the average of the individual assessments.
Other information
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