BIOCHEMISTRY
cod. 00061

Academic year 2017/18
3° year of course - Second semester
Professor
Davide FERRARI
Academic discipline
Biochimica (BIO/10)
Field
Discipline chimiche organiche e biochimiche
Type of training activity
Characterising
48 hours
of face-to-face activities
6 credits
hub: PARMA
course unit
in ITALIAN

Learning objectives

Knowledge of the fundamental properties of the biological macromolecules and of their structural- functional relationship. Knowledge of the processes of degradation and biosynthesis of the main classes of biomolecules, of the mechanisms of biological reaction and of their regulation, with particular attention to the application of the fundamentals of the chemistry (i.g. reversible reactions, redox potential, nucleophilic and electrophilic reactions, reaction rate). The student will be able to autonomously apply these knowledges to the study of others biological reactions and processes.

Prerequisites

To have acquired the necessary knowledges in the basic courses in Physics, Mthematics
General Chemistry and Organic Chemistry

Course unit content

Properties of biomolecules: nucleotides and nucleic acids, carbohydrates, lipids, aminoacids and proteins. Structure and function of proteins. Biological membranes. Enzyme catalysis and kinetics. Introduction to the metabolism: coenzymes, high energy bonds, redox potentials. Catabolism of glucose. Metabolism of glycogen. Gluconeogenesis. Tricarboxilic acids cicle and related rections. Electron transport, oxidative phosphorilation and respiratory control. Photosynthesis. Lipid metabolism: Fatty acids oxidation, keton bodies, fatty acids biosynthesi, cholesterol. Metabolim of aminoacids: transamination reactions, urea cycle, PLP-dependent reactions. Nucleotides metabolism: ex-novo purines and pyrimidine biosinthesis.

Full programme

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Bibliography

Voet, Voet, Pratt, Fundamentals of Biochemistry


Horton, Moran, etc
Principi di Biochimica
Pearson

Teaching methods

classroom lectures

Assessment methods and criteria

Written examination

Other information

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2030 agenda goals for sustainable development

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