Learning objectives
The student is asked to understand and learn the content of the course. Attendance to lessons, which is mandatory, will allow the student to acquire appropriate skills to describe, communicate effectively, use independence of judgment and comment the major topics of the program.
Prerequisites
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Course unit content
Initially the course introduces the student to the molecular organization and function of sarcomere describing the molecular action of contraction.
The course continues describing the function of energy substrates during different kind of physical exercise and dissecting the fatigue at molecular level.
Metabolic interrelationships in tissues and organs: metabolism of carbohydrates, lipids and proteins. Metabolism during feeding, fasting and stress. The Skeletal Muscle, sarcomere and myofibrillar proteins: structural organization, Molecular mechanisms of nerve impulse conduction and muscle contraction. Energy for muscle contraction. Classification, properties and metabolism of muscle fibers. Distribution of the various types of fibers.
Sources of energy in the muscle. Energy substrates present in the muscle fibers. Aerobic and anaerobic metabolism: aerobic, anaerobic a-lactate and anaerobic lactate. Effects of physical exercise on glucose transport systems and the effect of training. Carbohydrate metabolism during exercise. Lipid metabolism during exercise. Amino acid and protein metabolism during exercise. Molecular signals and regulators of muscle fatigue. Training.
Full programme
Metabolic interrelationships in tissues and organs: metabolism of carbohydrates, lipids and proteins. Metabolism during feeding, fasting and stress. The Skeletal Muscle, sarcomere and myofibrillar proteins: structural organization, Molecular mechanisms of nerve impulse conduction and muscle contraction. Energy for muscle contraction. Classification, properties and metabolism of muscle fibers. Distribution of the various types of fibers. Sources of energy in the muscle. Energy substrates present in the muscle fibers. Aerobic and anaerobic metabolism: aerobic, anaerobic a-lactate and anaerobic lactate. Effects of physical exercise on glucose transport systems and the effect of training. Carbohydrate metabolism during exercise. Lipid metabolism during exercise. Amino acid and protein metabolism during exercise. Molecular signals and regulators of muscle fatigue. Training.
Bibliography
Nelson DL, Cox MM: I principi di Biochimica di Lehninger, Zanichelli, Bologna.
Caldarera CM, BIOCHIMICA SISTEMATICA UMANA, 2003, Clueb
Fondamenti di Nutrizione Umana. Di A Mariani Costantini, C Cannella e G Tomassi. Il Pensiero Scientifico Ed. Roma, 1999.
Teaching methods
The course will comprise oral lectures and seminars to deep single issues, and will make use of multimedia systems. During the lessons, students will have the opportunity to discuss the key aspects of the course. Teachers will be available throughout the duration of the course to answer questions and support students during their training with individual meetings by appointment.
Assessment methods and criteria
Evaluation will be with oral exam in the traditional way. The grade obtained will be considered by the commettee for final evaluation intergating all the information aquired along the evaluation steps.
Other information
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2030 agenda goals for sustainable development
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