Learning objectives
In the context of the integrated course, the course is proposed to supply to the students general concepts on the causes and the mechanisms that carry to the diseases. In particular, general knowledge about the chemical and physical causes of diseases, about the immunity and concepts of cellular pathology will be supply. More particularly, the student will have to acquire knowledge about inflammation, neoplasia, genetic diseases, genetic deafness, diabetes, atherosclerosis, diseases of the blood and alterations of the haemostasis
Prerequisites
Knowledge of anatomy, histology, biochemistry, physiology are required
Course unit content
Concepts of aetiology and pathogenesis
Chemical and physical causes of diseases
Genetic damage. Mutations.
Hereditary diseases
Modality of transmission of the pathological characters.
Monogenic hereditary diseases: examples.
Hereditary deafness
Chromosomic aberrations
Concepts and mechanisms of cellular pathology
Reversible and irreversible cellular damage.
Necrosis and apoptosis
Ischemic damage
Innate and acquired immunity
Inflammation
Signs and phenomena of the acute inflammation
Inflammatory exudates
Phagocytoses
Chemical inflammatory mediators
Chronic inflammation
The fever
Neoplasia
Nomenclature
Epidemiologia
Grading and staging
Differences between benign and malignant tumors
Neoplastic progression
Molecular bases of the neoplasie
Metastasis
Physiopatology of the blood and the haemostasis
Constitution of the blood
Haemostasis and its alterations
Diabetes
Atherosclerosis
Full programme
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Bibliography
One text chosen between the following
1. Spector e Axford, Introduzione alla Patologia Generale, CEA
2. Woolf, Patologia Generale – Meccanismi della malattia, Idelson-Gnocchi
3. Caruso e Licastro – Compendio di Patologia Generale. Casa Ed. ambrosiana
4. Pontieri, Patologia e fisiopatologia generale Ed. Piccin
Teaching methods
Frontal lesson with the use of supports audiovisual, argument in classroom with the students, supply of the audiovisual aids, talks with the student upon request.
Assessment methods and criteria
The final appraisal involves one oral verification according to the calendar of examination of the Integrated Course.
Other information
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