cod. 06030

Academic year 2012/13
1° year of course - Second semester
Academic discipline
Patologia generale (MED/04)
Scienze biomediche
Type of training activity
24 hours
of face-to-face activities
3 credits
hub: -
course unit
in - - -

Learning objectives

In the context of the integrated course, the course is proposed to supply to the students general concepts on the causes and the mechanisms that carry to the diseases. In particular, general knowledge about the chemical and physical causes of diseases, about the immunity and concepts of cellular pathology will be supply. More particularly, the student will have to acquire knowledge about inflammation, neoplasia, genetic diseases, genetic deafness, diabetes, atherosclerosis, diseases of the blood and alterations of the haemostasis


Knowledge of anatomy, histology, biochemistry, physiology are required

Course unit content

Concepts of aetiology and pathogenesis

Chemical and physical causes of diseases

Genetic damage. Mutations.

Hereditary diseases
Modality of transmission of the pathological characters.
Monogenic hereditary diseases: examples.
Hereditary deafness
Chromosomic aberrations

Concepts and mechanisms of cellular pathology
Reversible and irreversible cellular damage.
Necrosis and apoptosis
Ischemic damage

Innate and acquired immunity

Signs and phenomena of the acute inflammation
Inflammatory exudates
Chemical inflammatory mediators
Chronic inflammation
The fever

Grading and staging
Differences between benign and malignant tumors
Neoplastic progression
Molecular bases of the neoplasie

Physiopatology of the blood and the haemostasis
Constitution of the blood
Haemostasis and its alterations



Full programme

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One text chosen between the following

1. Spector e Axford, Introduzione alla Patologia Generale, CEA
2. Woolf, Patologia Generale – Meccanismi della malattia, Idelson-Gnocchi
3. Caruso e Licastro – Compendio di Patologia Generale. Casa Ed. ambrosiana
4. Pontieri, Patologia e fisiopatologia generale Ed. Piccin

Teaching methods

Frontal lesson with the use of supports audiovisual, argument in classroom with the students, supply of the audiovisual aids, talks with the student upon request.

Assessment methods and criteria

The final appraisal involves one oral verification according to the calendar of examination of the Integrated Course.

Other information

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