Learning objectives
The Course of Clinical Pathology is part of the Integrated Course of General and Clinical Pathology.
The course aims to enable students to know and understand the main laboratory tests, in order to achieve the ability to use the knowledge and understanding gained in identifying the patient's problems related to the disease.
Prerequisites
Mandatory propedeutic examinations are defined by the Course Council.
Relevant bases of Biochemistry, Physiology, Immunology and General Pathology should be adequately recalled.
Course unit content
The course will concern on the following content:
1.Generalia of clinical patholgy
2. Blood and cytometric exams
3.The laboratory in the diagnostic of anemias
4. Serum proteins
5.The laboratory in the evaluation of hemostatic function
6. Transfusion medicine
7. First level laboratory tests for the study of liver function
8. Laboratory tests for the study of kidney function
9.The laboratory in diabetes mellitus
10.The laboratory in cardiovascular diseases
11.The laboratory in respiratory diseases
12. Analysis of the cephalo-rachid fluid
13.Tumor markers
Full programme
Insertion of the Laboratory data in the diagnostic procedure and its functions in other optics such as prevention, prognosis, therapy and screening. Emergency exams and routines (examples)
Evaluation criteria of the analytical data
Factors that influence the reliability and interpretation of laboratory data:
Preanalytic variability
Analytical variability
Hematopoietic system
Hemochromocytometric examination
Evaluation of iron metabolism
Hemoglobin and Bilirubin
Laboratory diagnostics anemias and diseases white blood cells
Plasma proteins
Electrophoresis
Albumin and globulins
Meaning specific protein dosage
Dosage of plasma enzymes and hormones
Haemostasis
Evaluation of coagulation, fibrinolysis, platelet function
Major laboratory diagnostics coagulopathies
Hepatic system
Main hepatic enzymes
Bile and bilirubin
Jaundice and urea cycle
Renal system
Chemical-physical examination of urine
Osmolarity and specific weight
Dosing of the main electrolytes
Uriemia, azotemia, creatinine (and clearance)
Proteinuria, glycosuria, hemoglobinuria, hematuria
Endocrine system
Diabetes laboratory diagnostics
Cardiovascular system
Cardiac ischemia markers
Respiratory System
hemogasanalysis
Tumor markers
Bibliography
G. Federici: Medicina di laboratorio – McGraw – Hill (last edition)
Widmann: Interpretazione clinica degli esami di laboratorio – McGraw – Hill (last edition)
M. Ciaccio, G. Lippi: Biochimica Clinica e Medicina di Laboratorio - EdiSes (last edition)
The slides used during the lectures will be made available on the Elly Platform.
Teaching methods
The course will be performed through interactive lectures in front of the students, with the aid of illustrative material that, at the end of the course, will be made available to students on Elly site at the pages of the course.
Lectures will be held on-site in compliance with safety standards, if further instructions are not implemented.
During the lessons we will discuss the issues related to laboratory tests and their interpretation topic will be exposed, encouraging students to ask questions on the basis of references that will be provided.
Assessment methods and criteria
Verification tests in progress will not be carried out.
Final assessment will be carried out through oral examination (with other teachers of the integrated course), during which one question will concern the topics of Clinical Pathology.
The exam will aim to evaluate the communication and learning skills of the student, as well as his/her ability to judge the health status of the hypothetical patients.
Students with SLD / BSE must first contact “Il centro accoglienza e inclusione” (https://www.cai.unipr.it/)).
Each student will be asked questions on topics listed in the extended program. The inability to answer a question (or at least ascertained inability to provide a correct definition of the pathological phenomenon subject of the application) will result in not passing the exam.
The student will be evaluated with votes ranging from 0 to 30, with 18 being the lowest vote to positively pass the exam. The final vote will be decided by mutual agreement among the teachers of the integrated course.
Other information
