BASES OF THE IMMUNE RESPONSE
cod. 1009899

Academic year 2022/23
2° year of course - First semester
Professor
- Martina CHIU
Academic discipline
Patologia generale (MED/04)
Field
Attività formative affini o integrative
Type of training activity
Related/supplementary
20 hours
of face-to-face activities
2 credits
hub: PARMA
course unit
in ITALIAN

Integrated course unit module: GENERAL AND CLINICAL PATHOLOGY

Learning objectives

Once completed the course and acquired the corresponding CFUs, the
student will be able:
- to understand the mechanisms of the innate and acquired immune response;
- to apply this knowledge to understand human pathologies of interest in dentistry

Prerequisites

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Course unit content

Lectures will concern the following main subjects:
Nomenclature and components of the immune system.
General characteristics of immune responses.
Mechanisms of innate immunity and adaptive immunity.
Autoimmunity and immunodeficiency,
Reactions of hypersensitivity.

Full programme

Innate immunity: Phagocitosis; Complement activation.
Specific Immunity: Cell-mediated Immunity. Antigen recognition and effector functions of T lymphocytes. The Major Histocompatibility Complex.
Humoral Immunity. Immunoglobulin types. Antigen recognition and effector functions of immunoglobulins. The memory of immune system.
Immunological tolerance. Loss of tolerance and autoimmunity. Immunodeficiencies.
Hypersensitivity reactions (I-IV), with clinical examples (allergic reactions; transplant rejection).

Bibliography

Abbas-Lichtman-Pober "Immunologia cellulare e molecolare" Ed. PICCIN
Mak-Saunder "Fondamenti di Immunologia" Ed. ZANICHELLI

Teaching methods

Lessons will be on site in compliance with safety standards, provided that further instructions on the ongoing health emergency are not implemented. Supporting didactic material will be available on the specific, student-reserved platform (Elly) and will include slide presentations, audio-video aids or video-recording of the lessons.
Slides are to be considered an essential, yet NOT exhaustive, didactic
resource.
Lessons will concern the main conceptual frame of each subject,
summoning questions or doubts from the audience and indicating
bibliographic references for deepened study of the subject.
Students who cannot attend the lectures are warmly invited to check
regularly the Elly Platform for didactic material and communications.

Assessment methods and criteria

The degree of learning will be assessed at the end of the course through oral examination to establish the learning outcomes on the bases of the proposed objectives. In particular, the student will be able to know the essential bases of immune response and to understand the mechanisms that regulate this response. The student will be evaluated with votes ranging from 0 to 30, with 18 being the lowest vote to positively pass the exam. The final vote will be decided by mutual agreement among the teachers of the integrated course. In case of the persistence of the health emergency, the exams will be conducted remotely, as follows: remote oral questions, through the Teams platform (guide http://selma.unipr.it/).
Students with SLD / BSE must first contact Le Eli-che: support for students with disabilities, D.S.A., B.E.S. (https://sea.unipr.it/it/servizi/le-eli-che-supporto-studenti-con-disabilita-dsa-bes)

Other information

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