cod. 1009033

Academic year 2020/21
1° year of course - First semester
- Paolo GOVONI - Stefano GUIZZARDI
Academic discipline
Istologia (BIO/17)
Morfologia umana, funzioni biologiche integrate degli organi ed apparati umani
Type of training activity
70 hours
of face-to-face activities
7 credits
hub: PARMA
course unit

Integrated course unit module: HISTOLOGY AND EMBRYOLOGY

Learning objectives

The target of the course is to allow the student to know and to understand the essential elements of the tissues and organs structure. The student will utilize knowledge and understanding for Anatomy and Physiology future study.
At the end of the course the student will demonstrate knowledge and understanding about: Cell structute and organization, Tissue structure and organization, Multi tissutal units structure and organization.


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Course unit content

In the first part of the course will be developed the functional and structural aspects of living substance and its capability of aggregations to form cells. Successively will be illustrated the structural and functional aspects of the different cells. In the second part of the course will be analyzed the modality of development of the cells toward the embryonic development. In the third part of the course the structural and functional aspects of the different tissues will be analyzed together with their capacity of aggregation on form multi tissue units and organs.

Full programme

The cell. Chemical and physical aspects. biological properties
The extracellular matrix. Chemical and physical aspects. Biological properties. Morpho-functional
The cell as a thermodynamic system. The cell system as planned. The cell as a chemical environment. The cell as a physical environment. The bacterial cell. The plant cell. The animal cell
The supracellular units. The fabrics. Organs. The apparatus and systems
Fundamentals of technology. Analytical methods and biochemical methods histochemical investigation. Microscopy investigation of the morphology. The microscopes. Utility and technical limitations of the various microscopes. The histological stable. Preparation of histological stable
Principles of reading a histological preparation
The biomolecules. Morpho-functional aspects and location, humans, water, minerals, carbohydrates, lipids, proteins and nucleic acids
The supramolecular complexes. Stable supramolecular complexes. Labile supramolecular complexes.
The organs and systems of the cell. The cytoplasmic matrix. The cell periphery. The nucleus. Ribosomal subunits, ribosomes, polysomes and endoplasmic reticulum. The Golgi complex. The complexes endosomal. The vesicles and vacuoles. The peroxisomes. The mitochondria. Centrosome, mitotic spindle and asters
The cell cycle. The mitotic cell cycle. The meiotic cell cycle. Cell cycle kinetics
Cell senescence. The cell death
Somatic cells and germ cells
Stem cells and differentiated cells. The cell populations.
Embryonic development. The stages of development. Differentiation and growth
Morphological aspects of development. The week of development. II week of development. III week of development. IV week of development. II-III months of development. II-III trimester of development. Genetics of morphogenesis


The main books adopted are:
-M. Mattioli Belmonte et al. ISTOLOGIA UMANA; Casa Editrice Idelson-Gnocchi, ed. 2021
-NM Maraldi et al. ISTOLOGIA MEDICA; Casa Editrice Edi Ermes ed. 2016
-NM Maraldi et al. BIOLOGIA-CITOLOGIA MEDICA; Casa Editrice Edi Ermes ed. 2016
A.L. Kierszenbaum, L.L. Tres ISTOLOGIA Dalle basi molecolari alle correlazioni cliniche; Casa Editrice EDRA, ed. 2020
-G. Bertini et al. EMBRIOLOGIA UMANA; Casa Editrice Idelson-Gnocchi, ed. 2019

Teaching methods

The course will be held through lectures to Students in the classroom (“in presenza”) or in synchronous-streaming (“in telepresenza”) on the Teams platform in case of the persistence of the health emergency. Therefore, the opportunity of Student/Teacher interaction will be preserved both face to face and remotely, by the simultaneous use of the Teams platform.
Lectures will be supported by slide presentations, which will be available to students on the Elly platform (https://elly2020.medicina.unipr.it/).

Assessment methods and criteria

Oral examination.
In case of the persistence of the health emergency, the exams will be conducted remotely, as follows:
remote oral questions, through the Teams platform (guide http://selma.unipr.it/).
Students with SLD / BSE must first contact Le Eli-che: support for students with disabilities, D.S.A., B.E.S. (https://sea.unipr.it/it/servizi/le-eli-che-supporto-studenti-con-disabilita-dsa-bes)

Other information

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