TOXICOLOGY
cod. 03033

Academic year 2014/15
4° year of course - First semester
Professor
Academic discipline
Farmacologia (BIO/14)
Field
Discipline biologiche e farmacologiche
Type of training activity
Characterising
72 hours
of face-to-face activities
9 credits
hub: PARMA
course unit
in - - -

Learning objectives

Provide knowledge about the nature of toxic effect of xenobiotics.

Prerequisites

- - -

Course unit content

toxic action of xenobiotics and the main regulatory aspects;

Full programme

General Section

· General principles of toxicology.

· Mechanisms of toxicity. Toxicity test.

· Absorption, distribution and excretion of toxic substances.

· Biotransformation of xenobiotics.

· Carcinogenesis, teratogenesis, mutagenesis.

 

special section

· Experimental toxicology and toxicological risk assessment.

· Idiosyncratic reactions and allergic diseases, interactions between xenobiotics.

· Toxicology of pesticides, metals, solvents, pesticides, PAHs, PCOD, PCB, plant and animal toxins.

· Environmental Toxicology: air pollution, water and soil.

· Toxicology food and nutrition: Food Additives and Contaminants. Regulatory bodies.

· Occupational Toxicology

· Toxicology of biotechnology products.
 
· Toxicology of principal organs.

Bibliography

teacher's slides

-ERNEST HODGSON: “Tossicologia Moderna”, EdiSES

-CASARETT & DOULL’S: "Tossicologia: fondamenti dell’azione delle sostanze tossiche", Ed. EMSI,

Roma.

-W.A. HAYES: "Principles and Methods of Toxicology", III Edition, Raven Press.

-C.L. GALLI, E. CORSINI, M. MARINOVICH “Tossicologia”, Piccin

Teaching methods

classroom

Assessment methods and criteria

oral examination

Other information

- - -