Learning objectives
Knowledge and understanding skills
1) To acquire the basic notions of pharmacology and pharmacotherapy 2) To acquire preliminary pharmacokinetic and pharmacodynamic notions for understanding the pharmacological activity of drugs.
3) To know the pharmacological activity of the main drugs for cardiovascular prevention and their mechanisms of action
To know the new technologies used in prevention and therapy of some neurological diseases (immunotherapy with construction of a recombinant antigen, therapeutic applications of neural stem cells).
To know the Laboratories Technologies of human gametes handling
4) To Acquire ability in using the specific language of the discipline.
Knowledge and understanding applied skills
1) To apply the knowledge of the mechanisms of action of drugs and of the new therapeutic technics to define their use in prevention and therapy.
Judgment autonomy
1) To evaluate, in independent manner, the validity of cardiovascular prevention strategy, the new therapeutic technics for neurological diseases, and infertility.
Communicative Skills
1) Possess the ability to synthesize information and effectively communicate it to specialists and non-specialists.
Learning Skills
1) Develop skills and methodology that will allow you to study in a highly indipendent way.
2) Updating the knowledge through the consultation of scientific databases
Prerequisites
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Course unit content
General pharmacology principles
- Pincipal classes of drugs
- Prevention of cardiovascular disease
- Antihypertensive and anticoagulant drugs, hypolipidemic drugs, drugs for diabetes and obesity
new strategies for prevention and therapy of Alzheimer's disease. Prevention of ischemic stroke. Stem cells in Parkinson's disease, Multiple Sclerosis and Amyotrophic Lateral Sclerosis. Prevention and therapy of damage arising from spinal cord injury. Dystrophinopathies.
Assisted Reproductive Technologies
Full programme
General Pharmacodynamic and Pharmacokinetic Principles
Quantal and gradual responses
Eficacy and Potenzy
Drug interactions
ADME
Repeat dose kinetics
Epidemiology
Cholesterol and lipoprotein metabolism
Global cardiovascular risk
Hypolipidemic drugs
antihypertensive
antiplatelet agents
anticoagulants
Drugs for obesity
Non-pharmacological Approaches to Cardiovascular Prevention,
Prevention and treatment of Alzheimer's disease. Prevention of ischemic stroke. Stem cells in Parkinson's disease, multiple sclerosis and amyotrophic lateral sclerosis. Prevention of damage and therapy in spinal traumas. Distrofinopathies.
New technologies used in the prevention and treatment of some neurological diseases: vaccines produced by genetic engineering, therapeutic applications of stem cells
Medication assisted Procreation Techniques
Laboratory techniques for the manipulation of gametes
Bibliography
GOODMAN & GILMAN’S: "The pharmacological basis of therapeutics"
Human stem cells for CNS repair. R. Zietlow, E.L. Lane, S.B. Dunnet, A.E. Rosser. Cell Tissue Res (2008), 331: 301-322.
Stem cells and neurological diseases. D.C. Hess and C.V. Borlongan. Cell Prolif. (2008), 41 (Suppl.1), 94-114.
Documents provided by the teachers
Teaching methods
Oral lessons
Assessment methods and criteria
Oral examination, Scale of assessment: 0-30
Weights and evaluation criteria:
1) Acquired knowledge (up to 16/30);
2) Ability to apply the acquired knowledge and to make connections between the covered topics (up to 9/30);
3) capacity to communicate concepts through the use of the specific language of the discipline (up to 5/30).
Other information
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