Learning objectives
Taking into account the previously acquired knowledge of anatomy, biology, biochemistry, physiology, and general pathology, at the end of the course the student must demonstrate understanding about:
the general principles of pharmacokinetics and pharmacodynamics,
the route of administration of drugs and the properties of the different pharmaceutical forms,
the concept of bioavailability and bioequivalence,
the correct procedures and timing of drug administration,
the causes, signs and symptoms of major adverse events of drugs,
the consequences and treatment of drug-drug interactions and interaction of medicaments with substances of herbal and alimentary origin,
the instructions for use of the different classes of drugs most commonly used in diseases of obstetric-gynecologic and surgical interest.
Even in cooperation with other professionals, the student will then be able to:
contribute to the success of the therapy prescribed
identify the problems related to drug therapy
prepare an appropriate care plan.
Prerequisites
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Course unit content
Outcomes of the course.
The module of Pharmacology is included in the Integrated Course of "GENERALMEDICINE". The teaching of Pharmacology aims to educate the student to the knowledge and understanding of the mechanisms of drug action and the basic principles that govern the movement of drugs in the body. The student will use knowledge about the use of drugs in obstetric-gynecologic therapy and / or in the management of natural or assisted childbirth.
Full programme
General concepts on drugs. Nomenclature, pharmaceutical forms, discovery and development of new drugs, drug prescription. Pharmacosurveillance.
General principles of pharmacokinetics. Absorption, distribution, metabolism and elimination of drugs. Accumulation of drugs into the body.
Routes of administration of drugs
Bioavailability and Bioequivalence.
Dosage of drugs and Therapeutic Regimens
Principles of Pharmacodynamics: mechanism of drug action and molecular targets.
Factors that modify the response to drugs
Drug toxicity: intolerance and allergy. Idiosyncratic responses and principles of pharmacogenetics.
Drug-drug interactions of clinical relevance.
Drugs acting on the central nervous system. Benzodiazepines, antidepressants, adrenergic stimulants.
Drugs for control of pain. Opioid analgesics. Local anesthetics. NSAIDs and acetaminophen.
Competitive and depolarizing neuromuscular blockers. Botulinum toxin and direct antispasmodics.
Steroidal anti-inflammatory drugs and immunosuppressants: focus on corticosteroids.
Gastrointestinal drugs: antacids, histamine H2-receptor antagonists, proton pump inhibitors, antiemetics, prokinetics, anti-diarrhoics, laxatives.
Cardiovascular drugs, antihypertensives, diuretics, antiarrhythmics, digitalis and other positive inotropes; coronaroactive drugs, drugs affecting hemostasis.
Drugs affecting the reproductive system and uterine motility.
General concept of drug therapy of the infective states: antibacterials and antibiotics.
Bibliography
Compendio di Farmacologia generale e speciale. Amico-Roxas et al. U T E T , 2 0 1 2.
Farmacologia generale e speciale per le Lauree sanitarie. Di Giulio et al. P I C C I N, 2 0 1 8
Fondamenti di Farmacologia per infermieri. Clayton and Stock, 2012
(Consider more recent editions, if available).
Teaching methods
The course will be held through lectures. In case the COVID-related emergence continues, frontal lessons will proceed remotely through the Teams platform (for instructions, see http://selma.unipr.it). Lessons will be carried out with the aid of iconographic material collected in PowerPoint files that, at the end of the course, will be made available to students on the Elly site at the course pages.
Assessment methods and criteria
Oral examen.
In case of the persistence of the health emergency, the exams will be conducted remotely, as follows:
remote oral questions, through the Teams platform (guide http://selma.unipr.it/).
Students with SLD / BSE must first contact Le Eli-che: support for students with disabilities, D.S.A., B.E.S. (https://sea.unipr.it/it/servizi/le-eli-che-supporto-studenti-con-disabilita-dsa-bes)
Other information
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