Learning objectives
Aim of the course is to the student to distinguish a mechanic or inflammatory pain, to know the classification of the rheumatic diseases and the main manifestations of rheumatic disorders, other than to be able to make a differential diagnosis among them.
The course aims also to provide short notes on the drugs used for the treatment of rheumatic diseases, with a careful attention on more recent biotechnological drugs, and on the treatment strategies in rheumatology.
Prerequisites
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Course unit content
The term “rheumatic diseases” encompass a large number of pathologic conditions characterized by pain and musculo-skeletal involvement. Rheumatic diseases are very heterogeneous, including inflammatory or degenerative, inherited or acquired, mechanic or immune-mediated conditions.
Full programme
- Classification and definition of rheumatic diseases
- Role and significance of autoimmunity
- Osteoarthritis
- Fibromyalgia
- Gout
- Chondrocalcinosis e microcrystalline arthropathies
- Chronic inflammatory arthritis:
Rheumatoid arthritis
Seronegative spondylarthritis: ankylosing spondylitis, entero-arthritis, non-radiographic spondylarthritis
Psoriatic arthritis
Reactive and infectious arthritis
- Connective tissue diseases:
Systemic lupus erythematosus and anti-phospholipid antibody syndrome
Systemic sclerosis and Raynaud’s phenomenon
Sjogren’s syndrome
Inflammatory idiopathic myopathies: dermatomyositis, polymyositis, anti-synthetase antibodies syndrome
Mixed connective tissue disease
Undifferentiated connective tissue disease
- Systemic vasculitis
Giant cell arteritis and polymyalgia rheumatica
Takayasu’s arteritis
Polyarteritis nodosa
ANCA associated vasculitis: granulomatosis with polyangiitis, micro-polyangiitis, eosinophilic granulomatosis with polyangiitis
Cryoglobulinaemic vasculitis
IgA vasculitis
- Autoinflammatory diseases, definition and classification:
Behcet’s disease
Familial mediterranean fever
- Bone diseases:
Osteoporosis
Paget’s disease
Bibliography
Reumatologia, Edilson-Gnocchi IV edition, 2018
Core curriculum. Reumatologia, McGraw-Hill Education, I edition, 2014
Teaching methods
Frontal lessons, presentation and discussion of clinical cases
Assessment methods and criteria
Esame orale
Other information
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