Learning objectives
CLINICAL MICROBIOLOGY
Principles and methods for the laboratory diagnosis of infectious diseases
Aetiology, outline of pathogenesis, clinical samples, laboratory diagnostic
procedures, interpretation of the results of microbiological and virological
investigations to diagnose the infectious diseases.
The determination of susceptibility/resistance of the pathogenic agents to
chemotherapeutics
CLINICAL PATHOLOGY
To know the most relevant laboratory tests
To understand the role and the importance of the laboratory medicine for a correct
diagnosis
To evaluate cost/benefit ratio
CLINICAL BIOCHEMISTRY
To correctly apply the fit methodologies to notice the functional finds and of
laboratory, critically also interpreting them under the physiopathologix profile, to the
goals of the diagnosis and the prognosis. The student has to be able to point out for
the clinical cases of different typology, brought to his/her observation, the more
appropriate investigations of laboratory, to appraise of it critically the diagnostic
meaning and to suggest the more effective close examinations of laboratory.
Prerequisites
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Course unit content
CLINICAL MICROBIOLOGY
Principles and methods for the laboratory diagnosis of infectious diseases -
Demonstration of the pathogenic agent and its constituents in the pathological
material - Demonstration of a recent specific immune response - The medical
prescription of microbiological and virological investigations - Collection, transport
and preservation of the clinical samples for microbiological and virological
investigations - Aetiology, outline of pathogenesis, clinical samples, laboratory
diagnostic procedures, interpretation of the results of microbiological investigations
regarding the diagnosis of:
Infections of the respiratory apparatus - Infections of the intestinal apparatus and
related glands - Systemic infections - Infections of the cardiovascular apparatus -
Infections of the central nervous system - Infections of the genitourinary apparatur
and sexually - transmitted infections - Infections of the skin and cutaneous adnexa -
Infections of the muscular-skeletal apparatus - Infections of the eye and the earprenatal,
connatal and perinatal infections - The nosocomial infections - The
determination of susceptibility/resistance of the pathogenic agents to
chemotherapeutics - Methods - Interpretation of the results - The dosage of
chemotherapeutics in tissues and biological fluids.
CLINICAL PATHOLOGY
Laboratory tests, patient preparation, biological samples - Hematological laboratory
test and their interpretation in the diagnosis of hematological diseases - Endocrine
and metabolic test and their interpretation - Tumour markers and their interpretation
- Diagnostic molecular biology.
Full programme
CLINICAL MICROBIOLOGY
Principles and methods for the laboratory diagnosis of infectious diseases -
Demonstration of the pathogenic agent and its constituents in the pathological
material - Demonstration of a recent specific immune response - The medical
prescription of microbiological and virological investigations - Collection, transport
and preservation of the clinical samples for microbiological and virological
investigations - Aetiology, outline of pathogenesis, clinical samples, laboratory
diagnostic procedures, interpretation of the results of microbiological investigations
regarding the diagnosis of:
Infections of the respiratory apparatus - Infections of the intestinal apparatus and
related glands - Systemic infections - Infections of the cardiovascular apparatus -
Infections of the central nervous system - Infections of the genitourinary apparatur
and sexually - transmitted infections - Infections of the skin and cutaneous adnexa -
Infections of the muscular-skeletal apparatus - Infections of the eye and the earprenatal,
connatal and perinatal infections - The nosocomial infections - The
determination of susceptibility/resistance of the pathogenic agents to
chemotherapeutics - Methods - Interpretation of the results - The dosage of
chemotherapeutics in tissues and biological fluids.
CLINICAL BIOCHEMISTRY
To begin to apply the logical tools in the clinical reasoning and to address the
choices of the diagnostic tools according to the decisional criterions of efficiency
and effectiveness tha keep in mind of the relationships among benefits, risks and
costs.
Preanalytical, analytical and postanalytical variability. Condition tha can alter results
of the analyses of laboratory; different possibilities of collecting - Correct application
of the techniques for the collecting and the harvest of the materials. - The concept
of normality in biology and the functions of risk (normal values on statistic base,
normal values on biological base, desirable values and functions of risk, usable
decisional values to diagnostic or therapeutic end). - General principles of the most
diffused techniques in use near the clinical laboratories. Control of quality - To
appraise critically a report (intervals of reference, sensibility and specificity of a test,
predictive value, critical difference) The values of reference of the analyses of the
common routine - Elements of diagnostic molecular - Investigations for the control
of the pregnancy - Interpretation of the complete examination of the urines in key of
diagnostic use - Interpretation of measures of enzymes and isoenzymes, and of
other indicators as diagnostic mean in specific pathologies and of organ -
Alterations biochemical-clinics in the carbohydrate metabolism - Alterations
biochemical-clinics in the lipid metabolism - Alterations biochemical-clinics in the
purine metabolism - Alterations biochemical-clinics in the electrolytes - Alterations
biochemical-clinics in the mineral metabolism and the connected pathologies -
Interpretation of the parameters of the equilibrium acid-base in ralationship to their
pathologies. To orient on the choice and on the meaning of the principal diagnostic
tests in the most common endocrine pathologies - Interpretation of the alterations of
the plasma proteins as suspect diagnostic of the pathologies to them connect.
CLINICAL PATHOLOGY
Laboratory tests, patient preparation, biological samples - Hematological laboratory
test and their interpretation in the diagnosis of hematological diseases - Endocrine
and metabolic test and their interpretation - Tumour markers and their interpretation
- Diagnostic molecular biology.
Bibliography
M.Bendinelli, A. Calderaro, C. Chezzi, G. Dettori, N. Manca, G. Morace, L. Polonelli, M.A. Tufano - - Monduzzi Editore - 2006-2012 - Microbiologia Medica: Batteriologia, Micologia, Parassitologia, Virologia. Gli agenti infettivi dell'uomo: biologia, azione patogena, laboratorio.
Teaching methods
Oral lessons and practical lesson in clinical diagnostic laboratories.Lectures will be held on-site in compliance with safety standards, provided that further instructions on the ongoing health emergency are not implemented. Supporting material will be available on the specific, student-reserved platform (Elly) and will include slide presentations, audio-video aids or video-recording of the lectures.
Assessment methods and criteria
Oral examination
Other information
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2030 agenda goals for sustainable development
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