cod. 1002376

Academic year 2017/18
3° year of course - Second semester
Professor responsible for the course unit
DI MARIO Francesco
integrated course unit
8 credits
hub: PARMA
course unit

Learning objectives

Differential diagnosis of main digestive and endocrinological diseases


According with rules of School of Medicine

Course unit content

Basic knowledge of main pathophysiological, diagnostic and clinical features of digestive and endocrinological diseases

Full programme

1) Esophagus: Elements of anatomy with particular reference to the upper and lower esophageal sphincters, physiology and pathophysiology elements with particular reference to motor functions, esophageal motility disorders: dyskinesias (classification, clinic, diagnosis), achalasia (epidemiology, pathophysiology, clinical , diagnosis, therapy), esophageal diverticula: pulsion (pathogenesis, clinical, complications, diagnosis, therapy), traction and epifrenici (definition and clinical) diverticula, benign tumors (classification, clinic, therapy), malignant tumors (epidemiology, etiology, clinical, diagnosis, staging, therapy), gastro-oesophageal reflux (epidemiology, etiology, clinic, diagnosis, therapy), Barrett's esophagus (epidemiology, etiology, clinical, diagnosis, staging, therapy).
2) Diaphragma: diaphragmatic hernias: classification, hiatal hernia (anatomy of the hiatus joint and gastro-oesophageal, definition, epidemiology, classification), paraesophageal hernia (etiology, clinic, diagnosis, therapy), slipped hernia (etiology, clinic, diagnosis , therapy).
3) Stomach: Elements of anatomy, dyspeptic Disease (epidemiology, pathophysiology, clinical, diagnosis, therapy), Helicobacter pylori infection (diagnosis, H.P.-related gastritis, therapy), gastritis (etiology and classification), ulcers and surgical complications (bleeding, perforation, penetration, stenosis),, precancerous conditions and tumors (epidemiology, etiology, clinical, diagnosis, staging, therapy, prognosis): adenocarcinoma, lymphoma and neuroendocrine tumors.
4) Pancreas: Elements of anatomy and physiology, Acute Pancreatitis (classification, epidemiology, etiology, pathophysiology, clinical, complications, diagnosis, therapy) signs, chronic and autoimmune pancreatitis (classification, epidemiology, etiology, pathophysiology, clinical complication, diagnosis, therapy), pancreatic exocrine tumors (epidemiology, etiology, clinical, diagnosis, staging, pancreatic pseudocysts (definition, etiology, development, clinical, complications, diagnosis, therapy), hormone-secreting tumors (classification, clinical diagnosis, therapy).
5) Biliary tract: Jaundice and cholestasis (definition, etiology, classification, clinic, differential diagnosis, therapy), Calculus of gallbladder and biliary tract (definition, epidemiology, pathophysiology, clinical, complications, therapy), cholecystitis and acute cholangitis (classification, etiology, clinic, diagnosis, therapy) and their complications nods (biliary-digestive fistula, gallstone ileus, benign and malignant stenosis (classification, etiology, clinic, diagnosis, therapy), neoplasms of the gallbladder and biliary tract ( etiology, clinic, diagnosis, therapy), immune-mediated disorders of the bile ducts (primary sclerosing cholangitis and primary biliary cirrhosis (classification, etiology, clinic, diagnosis, therapy).
6) Liver: steatosis, NASH and NAFLD, liver cirrhosis (classification, epidemiology, etiology, clinic, diagnosis, complications, therapy), Wilson's disease and hemochromatosis, hepatitis drug, autoimmune diseases of the liver, benign tumors (classification, epidemiology, clinic, diagnosis, therapy) nods, primary malignant tumors (classification, epidemiology, etiology, clinic, diagnosis, staging, signs of therapy), liver metastases (clinical, diagnostic, therapy).
7) Portal hypertension: Elements of anatomy macroscopic and microscopic of the portal system, pathophysiology, etiology. Esophageal varices (definition, pathological anatomy, classification, diagnosis, bleeding complications, clinical, endoscopic and surgical therapy), splenomegaly and hypersplenism (definition, clinic, therapy), ascites (definition, etiology, clinic, diagnosis, therapy) .
8) Small Intestine: Coeliac disease (Classification, epidemiology, etiology, clinic, diagnosis, complications), malabsorption (classification, epidemiology, etiology, clinic, diagnosis), benign and malignant tumors (classification, etiology, clinic, diagnosis, therapy , prognosis), Meckel's diverticulum (epidemiology, pathogenesis, clinical, complications, therapy)
9) Inflammatory bowel disease: Crohn's Disease (classification, epidemiology, etiology, clinic, diagnosis, complications, therapy), ulcerative colitis (classification, epidemiology, etiology, clinic, diagnosis, complications, therapy), indeterminate colitis, SCAD.
10) Vermiform appendix: Acute appendicitis (epidemiology, etiology, clinical, complications, diagnosis and therapy); tumors (classification, clinic, diagnostics, treatment)
11) Colon and rectus: Elements of anatomy and physiology; intestinal microbiota; Irritable Bowel Syndrome (classification, epidemiology, etiology, clinic, diagnosis, therapy); diverticular disease (definition, epidemiology, etiology, pathology, evolution and complications, clinical, diagnostic, therapy, surgical indications); constipation and diarrhea (pathophysiology, etiology, clinical, differential diagnosis, therapy); polyps (classification, epidemiology, clinical, diagnostic, development, therapy); familial polyposis (etiology, development, clinical, diagnostic, therapy); adenoma-carcinoma sequence; tumors (classification, epidemiology, etiology, clinic, diagnosis, therapy, screening, follow-up, prognosis).
12) Anus and perineum: elements of anatomy and physiology, hemorrhoids, anal fissure, perianal abscesses and fistulas (epidemiology, pathogenesis, classification, clinic, diagnosis, therapy); anus neoplasms (epidemiology, pathogenesis, clinic, diagnosis, treatment, staging).
13) Acute Abdomen: definition, pathophysiology of acute abdominal pain, causes according to the site, pain and symptoms associated with differential diagnosis. bowel obstruction: Mechanical and paralytic ileus (etiology, classification, pathophysiology, clinical, diagnosis, therapy). Peritonitis (etiology, classification, pathology, pathophysiology, clinical, diagnosis, therapy).
14) High And Low Digestive Bleeding: definition, etiology, classification, pathophysiology, clinical, diagnosis, therapy.
15) Intestinal ischemia: elements of anatomy of the intestinal vasculature, pathophysiology of the splanchnic arterial circulation, acute and chronic mesenteric ischemia (etiology, pathology, diagnosis, clinic, therapy).
16) Hernia of the Inguinal wall: elements of anatomy, definition, epidemiology, pathogenesis, clinical, complications, diagnosis, signs of inguinal hernia treatment, femoral hernia, umbilical hernia, epigastric hernia, hernia Spigelian, lumbar hernia, obturator hernia, incisional hernia.
1. General endocrinology 2. Pathophysiology and Endocrinology of hypothalamic diseases 3. Pathophysiology and Endocrinology of pituitary diseases. 4. Pathophysiology and Diseases of the Thyroid. 5. Pathophysiology and Diseases of the adrenal glands


Gastroenterology and Surgery: Manuale di Gastroenterologia Unigastro, Edizione 2016, E.G.I. editore

Endocrinology: Kumar & Clark’s, Clinical Medicine - 9th Edition or
Colao A., Giugliano D., Riccardi G. – Endocrinologia & Malattie del Metabolismo – 2° Edizione - Idelson-Gnocchi

Pathology: Robbins e Cotran - Le basi patologiche delle malattie, 8th Edition, Elsevier ed.
Vol. 1 Patologia generale - Vol. 2 Malattie degli organi e degli apparati

Teaching methods

Formal lessons, interactive activities, fellowship and addictional didatics

Assessment methods and criteria

Oral examination

Other information

- - -