Learning objectives
Knowledge and understanding of beneficial and toxic drug effect, aimed to a correct application of medicaments in the clinical setting.
Prerequisites
Knowledge and passing the exams of anatomy, biochemistry, phisiology and general pathology
Course unit content
Pharmacological properties of the different drug classes of specific use in the clinical setting
Full programme
Pharmacology of autonomic and somatic nervous system: cholinergic and adrenergic transmission.
Cholinergic drugs: direct and indirect agonists; muscarinic antagonists.
Adrenergic system drugs: specific receptor agonists and antagonists. Central adrenergic stimulants: cocaine, amphetamine or methylphenidate.
Ganglionic stimulant and blockers: nicotine and ganglioplegic drugs
Depolarizing and competitive neuromuscular blocking.
Central nervous system: general and local anesthetics, sedative-hypnotics, anxiolytics, antiepileptics, centrally-acting spasmolytics. Drugs for Parkinson and other neurodegenerative diseases. Antipsychotics and antidepressants.
Opioid and non-opioid analgesics. Compounds of abuse.
Chemotherapy: General definition, mechanisms of action, uses, resistance. Antimicrobials. Antivirals. Antifungals. Antineoplastic agents for chemiotherapy and novel drugs for target therapy.
Cardiovascular drugs: Anti-hypertensive, Antianginal, Antiarrhythmic treatments. beta blockers and other medications for congestive heart failure. Drugs for the treatment of dyslipidemia.
Drugs affectin the emostatic system: anticoagulants and antiplatelet agents. Fibrinolytics. The hematopoietic system drugs.
Kidney drugs. Diuretics and antidiuretics.
Drugs of the respiratory system. Antiasmatic and Antitussive treatments.
Gastrointestinal system drugs. Anti-ulcer and gastroprotective drugs. Drugs of intestinal motility: prokinetic and antispastic medicaments. Emetics, antiemetics. Laxatives.
Treatment of the inflammation: Anti-inflammatory drugs (NSAIDs and steroid). Drugs for chronic inflammations (ulcerative colitis, Crohn' disease, rheumatoid artritis).
Autacoids: Histamine and antihistamines. Serotonin and serotonin antagonists.
Endocrine pharmacology. Insulin and oral hypoglycemic. Glucocorticoids and mineralcorticoids. Estrogen and progestinic. Thyroid medications. Hypothalamic and pituitary hormones. Drugs for benign prostatic hypertrophy. Drugs for erectile dysfunction.
Bibliography
Rang, Dale et al., Pharmacology - Elsevier;
Katzung: Pharmacology (last ed.);
Goodman and Gilman: The pharmacological basis of therapeutics (last ed.)
