Learning objectives
The student should aquire the basic knowledge on the biologic, molecular and cellular events that have an impact on oncologic, hematologic and infectious diseases:
- Pathophysiology of hematopoiesis
- Control mechanisms of oncogenesis and tumor growth
- Stem cells and bone marrow transplantation
- Pathophysiology of the immune system
- The immune surveillance in onco-hematological and infectious diseases
Prerequisites
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Course unit content
Basic biologic, molecular and cellular mechanisms with clinical implication in oncologic, hematologic and infectious diseases:
- Pathophysiology of hematopoiesis
- Control mechanisms of oncogenesis and tumor growth
- Stem cells and bone marrow transplantation
- Pathophysiology of the immune system
- The immune surveillance in onco-hematological diseases
-Pathophysiology of common bacteric, viral and mycotic infections
-Cellular and tissue response to infective agents
Full programme
The student should know the pathophysiologic basis of the following diseases :
Hematologic
- Anemia , thrombocytopenia and leukopenia
- Aplastic anemia
- Myelodysplastic Syndromes
- Acute Leukemia
- Myeloproliferative Syndromes
-Lymphomas
-Multiple Myeloma and Monoclonal Gammopathies
Oncologic
- Malignancies: breast, lung, stomach, colorectal, kidney, prostate and ovary
Infectious
-hepatitis
- Tuberculosis
-HIVInfection
-Mononucleosic Syndromes
- Infections in the immunocompromised patient
Students must learn the basic principles of the clinical approach to the patient affected by hematologic, neoplastic and infectious diseases.
Setting the Diagnostic and Therapeutic Plan
- Interpretation of objective data and supporting laboratory and instrumental data
- The student must be familiar with the clinical features and elements of the differential diagnosis of palpable or radiologically proven neoplasms
- The student must be able to interpret haematologic indices, molecular studies and reports on microbiological and histological diagnosis
-Basic knowledge on clinical staging of the disease
- Interpretation of symptoms
- The student should recognize the specificity and clinical relevance of symptoms related to the disease
- The student must be familiar with the general clinical conditions influencing the approach to the patient affected by onco- hematological and infectious diseases.
- The student must be familiar with the methods of indexing the assessment of the performance status
- Participation of the student in the diagnostic workup of the patient
- assist the physician in performing diagnostic maneuvers: bone marrow fine needle aspiration and biopsy, lumbar puncture , paracentesis , and liver biopsy.
- Preparation and evaluation of cyto- morphological samples of peripheral blood and marrow aspiration.
The student needs to know how to set up, based on the clinical picture and available procedures, the correct diagnostic and prognostic evaluation of onco-hematological and infectious diseases
- The student must know the principles of treatment of onco-hematological and infectious diseases, and the clinical effects of therapeutic approaches:
- Chemotherapy
- Molecular targeted therapies
- Radiotherapy
-Bone marrow transplantation
- Antibiotic
- Anti- fungal
- Anti- viral
- Supportive Care
Bibliography
Textbooks are available on the description of each specific course
Teaching methods
lectures, training acitivities on specific ambulatories and clinical departments,seminars and more advanced courses
Assessment methods and criteria
oral test
Other information
Elective teaching courses are available
2030 agenda goals for sustainable development
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