Learning objectives
The Course of Clinical Pathology is part of the Integrated Course of Medical Sciences1.
The course aims to enable the student to know and understand the main laboratory tests, in order to achieve the ability to use the knowledge and understanding gained in identifying the patient's problems related to the disease.
Prerequisites
Basic knowledge of biology, cytology, histology and genetics is required to understand the topics covered in the course
Course unit content
The first lessons cover general topics regard to biological materials and preparation of the patient. The second part of the course addresses the main laboratory tests. The third part of the course covers the clinical interpretation of laboratory tests.
Full programme
Insertion of the Laboratory data in the diagnostic procedure and its functions in other optics such as prevention, prognosis, therapy and screening. Emergency exams and routines (examples)
Evaluation criteria of the analytical data
Factors that influence the reliability and interpretation of laboratory data:
Preanalytic variability
Analytical variability
Hematopoietic system
Hemochromocytometric examination
Evaluation of iron metabolism
Hemoglobin and Bilirubin
Laboratory diagnostics anemias and diseases white blood cells
Haemostasis
Evaluation of coagulation, fibrinolysis, platelet function
Major laboratory diagnostics coagulopathies
Cardiovascular system
Cardiac ischemia markers
Renal system
Chemical-physical examination of urine
Osmolarity and specific weight
Dosing of the main electrolytes
Uriemia, azotemia, creatinine (and clearance)
Proteinuria, glycosuria, hemoglobinuria, hematuria
Endocrine system
Diabetes laboratory diagnostics
Hepatic system
Main hepatic enzymes
Bile and bilirubin
Jaundice and urea cycle
Plasma proteins
Electrophoresis
Albumin and globulins
Meaning specific protein dosage
Dosage of plasma enzymes and hormones
Tumor markers
Bibliography
G. Federici: Medicina di laboratorio – McGraw – Hill (last edition)
Widmann: Interpretazione clinica degli esami di laboratorio – McGraw – Hill (ultima edizione)
Teaching methods
Frontal lessons. During the lessons will discuss the issues related to laboratory tests and their interpretation
Assessment methods and criteria
The assessment of the achievement of the objectives of the course will include in-course tests with multiple choice quiz. At the oral exam by questions regarding the contents of the course will be determined whether the student has achieved the goal of knowledge and understanding of the content and if it is able to apply the knowledge gained.
Other information
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2030 agenda goals for sustainable development
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