cod. 00152

Academic year 2010/11
2° year of course - Second semester
Academic discipline
Chimica organica (CHIM/06)
Discipline chimiche organiche e biochimiche
Type of training activity
48 hours
of face-to-face activities
6 credits
course unit

Learning objectives

To teach to the students the scientific methodology of Organic Chemistry<br />To provide the students with the bases to understand and explain the reaction mechanisms of the different mono and poli functional groups subjects of the course<br />To provide the students with the bases for the study of the structure and reactivity of the main classes of biomolecules<br />To show to students how a molecularly based approach can rationalise other related sectors such as Biology an Biotechnology;


To get through the examination of Organic Chemistry and Laboratory of Organic Chemistry I°

Course unit content

Module 1: Heteroaromaticity: aromaticity and antiaromaticity; five membered ring and six membered ring heterocicles;  reactivity, electrophilic aromatic substitution; fused rings<br />Module 2: Synthetic polimers: omopolimers and copolimers; condensation polimers and addition polimers; mechanisms of polimerisation; stereospecific polimers; biocompatible and biodegradable polimers<br />Module 3: Carbonyl compounds: nucleophilic addition; hydratation, reaction with alcohols, reaction with amines, reactions with carbon nucleophiles, Wittig reaction; nucleophilic addition to alfa-beta unsaturated carbonyl componds<br />Module 4: Carboxylic acids and derivatives: acidity; nucleophilic acylic substitution; carboxylic acid derivatives; electrophilic rearrangements; thioesters and mixed anhydrides; <br />Module 5: Reactions at the alfa carbon: keto-enol tautomerism; alfa alogenations; malonic and acetoacetic synthesis; aldolic condensation; Claisen condensation; Michael reaction; <br />Module 6: Amines: basicity; synthesis and reactivity; ammonium quaternary salts<br />Module 7: Carbohydrates: monosaccharides, disaccharides, polisaccharides; furanosic and pyranosic structures; stereochemistry, anomers, epimers; glicosidic bond; cellulose, amylose, glycogen<br />Module 8: Amino acids, peptides, proteins: structures, isoelectric points, reactivity; peptides, structure and synthesis;proteins, structure and function<br />Module 9: Lipids: triacylglycerols, waxes, steroids, terpenes<br />Module 10: Nucleic acids: mononucleosides and mononucleotides; purinic and pyrimidinic bases; DNA, RNA

Full programme

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J. McMurry, Organic Chemistry, Piccin Padova<br />- Brown and Foote, Organic Chemistry, Edises Napoli<br />- P. Vollhardt and N. Schore, Organic Chemistry, Zanichelli Bologna

Teaching methods

Frontal lectures and exercises

Assessment methods and criteria

Written examination and oral examination at the end of the course.

Other information

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