Learning objectives
The student should aquire the basic knowledge on the biology, molecular and cellular events that have an impact on oncologic, hematologic and infectious diseases:
- Pathophysiology of hematopoiesis
- Control mechanisms of oncogenesis and tumor growth
- Stem cells and bone marrow transplantation
- Pathophysiology of the immune system
- The immune surveillance in onco-hematological diseases
Prerequisites
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Course unit content
Basic biologic, molecular and cellular mechanisms of oncologic, hematologic and infectious diseases:
- Pathophysiology of hematopoiesis
- Control mechanisms of oncogenesis and tumor growth
- Stem cells and bone marrow transplantation
- Pathophysiology of the immune system
- The immune surveillance in onco-hematological diseases
Full programme
The student should know the pathophysiologic basis of the following diseases :
Hematologic
- Anemia , thrombocytopenia and leukopenia
- Aplastic anemia
- Myelodysplastic Syndromes
- Acute Leukemia
- Myeloproliferative Syndromes
-Lymphomas
-Multiple Myeloma and Monoclonal Gammopathies
Oncologic
- Malignancies: breast, lung, stomach, colorectal, kidney, prostate and ovary
Infectious
-hepatitis
- Tuberculosis
-HIVInfection
-Mononucleosic Syndromes
- Infections in the immunocompromised patient
Los student must learn the basics of the clinical approach to the patient hematologic, neoplastic and infectious :
Setting the Diagnostic and Therapeutic Plan
- Interpretation of objective data and supporting laboratory and instrumental
- The student must be familiar with the clinical features and elements of the differential diagnosis of neoplasms palpable or radiologically proven
- The student must be able to interpret haematological indices , molecular studies and reports at the end of the microbiological and histological diagnosis and clinical disease stadificazione
- Interpretation of symptoms
- The student should recognize the specificity and clinical relevance of symptoms related to the disease
- The student must be familiar with the clinical condition of internal influencing the approach to the patient onco- hematology - infectious
- The student must be familiar with the methods of indexing for the clinical assessment of performance status
- Participation of the student in the diagnostic workup of the patient
- Maneuvers diagnostic competence of the physician : fine needle aspiration and bone marrow biopsy , lumbar puncture , paracentesis , and liver biopsy.
- Evaluation of cyto- morphological prepared by drawing blood and agospirazione
The student needs to know to set up, based on the clinical picture , the correct diagnostic and prognostic evaluation of onco-hematological diseases - infectious using the principals available to achieve the same .
The student must know the principles of treatment of onco-hematological diseases - infectious and clinical effects of therapeutic approaches used :
- Chemotherapy
- Molecular targeted therapies
- Radiotherapy
- Transplantation of bone marrow
- Antibiotic Therapy
- Anti- fungal therapy
- Anti- viral therapy
- Supportive Care
Bibliography
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Teaching methods
lectures, training acitivities on specific ambulatories and clinical departments,seminars and more advanced courses
Assessment methods and criteria
oral test
Other information
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