1. Knowledge and understanding. At the end of the course, the student should be able to:
- Know how to classify proteins that are drug targets and recognize their specific functional and structural properties (Part I)
- Know and understand possible mechanisms of drug action from a biochemical point of view (Part I)
- Know and understand the main biochemical methodologies described in the course (Part II)
- Know and understand the principles of each methodology in molecular details (Part II)
- Know and understand the components of the instruments described in the course (Part II)
2. Applying knowledge and understanding. At the end of the course, the student should be able to:
- Identify the possible mechanism of action of a drug once its target is known (Part I)
- Recognize the possible mechanism of inhibition of an enzyme, based on the alteration of its kinetic parameters (Part I)
- Recognize the type of interaction between a drug and a receptor based on experimental observations (Part I)
- Identify the most suitable technique to obtain functional or structural pieces of information on macromolecules (Part II)
- Correctly represent a dataset graphically (Part II)
- Process simple datasets and their graphic representations to obtain structural and functional pieces of information (Part II)
- Query the biochemical databases illustrated in the course to retrieve information on proteins and genes (Part II).
3. Communication skills. At the end of the course, the student should be able to:
- Discuss the topics described in the course in a clear, concise and effective way.
- Describe the chemical structures of the main compounds and the mechanisms of enzyme and chemical reactions illustrated in the lectures (both Part I and Part II) with the correct scientific vocabulary.
- Describe any proteins in terms of secondary, tertiary and quaternary structure (Part II).
- Represent schematically the main biochemical techniques
4. Learning skills. At the end of the course, the student should be able to:
- make connections between the various topics of the course and those dealt with in other courses (particularly in the biochemical, pharmacological and physiological fields).
- Improve future knowledge on the main biochemical issues by querying databases
- Improve future knowledge by reading scientific publications (reviews)
- Understand the potential of research in biochemistry.