cod. 03033

Academic year 2011/12
3° year of course - First semester
Academic discipline
Farmacologia (BIO/14)
Discipline biologiche
Type of training activity
64 hours
of face-to-face activities
8 credits
hub: PARMA
course unit
in - - -

Learning objectives

To bring mechanisms and nature of toxic effects of drugs and xenobiotics to student's knowledge.


Pharmacology examination

Course unit content

General part

First principles of toxicity
Mechanisms and tests of toxicity
ADME of toxic substance
Metabolism of xenobiotics
Cancerogenesis, teratogenesis and mutagenesis

Special part

Experimental toxicology and evaluation of toxicological risks
Idiosincrasic and allergic reactions.
Interactions between xenobiotics
Metals, Solvents, Pesticides, IPA, PCOD, PCB
Enviromental toxicoogy
Alimentary toxicology
Occupational toxicology
Toxicology of biotecnological products
Toxicology of herbal products
Poisons and antidotes

Toxicology of:

Cardiovascular Sistem
Central Nervous Sistem (CNS)

Full programme

- - -


Recommended readings:
CASARETT & DOULL’S: "Tossicologia: I fondamenti dell’azione delle sostanze tossiche", 6° Edizione. Ed. EMSI, Roma.

Piera Ghi: “Tossicologia: principi e applicazioni all’uso dei farmaci e dei prodotti della salute”. Edizione Minerva Medica

C.L. GALLI, E. CORSINI, M. MARINOVICH “Tossicologia”. Edizione Piccin

W.A. HAYES: "Principles and Methods of Toxicology", III Edition, Raven Press.

GOODMAN & GILMAN’S: "The pharmacological basis of therapeutics"

ERNEST HODGSON: “Tossicologia Moderna”, EdiSES

Teaching methods

Oral lesson

Assessment methods and criteria

Oral examination

Other information

The oral examination will be about the entire program. Students have to show to have a good comprension of principal parts of each topic.