Learning objectives
To bring mechanisms and nature of toxic effects of drugs and xenobiotics to student's knowledge.
Prerequisites
Pharmacology exam.
Course unit content
<br />General part<br /><br />First principles of toxicity<br />Mechanisms and tests of toxicity<br />ADME of toxic substance<br />Metabolism of xenobiotics <br />Cancerogenesis, teratogenesis and mutagenesis<br />Special part<br /><br />Experimental toxicology and evaluation of toxicological risks<br />Idiosincrasic and allergic reactions. Interactions between xenobiotics<br />Metals, Solvents, Pesticides, IPA, PCOD, PCB<br />Enviromental toxicoogy<br />Alimentary toxicology<br />Occupational toxicology<br />Toxicology of biotecnological products<br />Toxicology of herbal products<br />Poisons and antidotes<br />Toxicology of:<br /><br />Lung<br />Kidney<br />Liver<br />Cardiovascular Sistem <br />Central Nervous Sistem (CNS)
Full programme
- - -
Bibliography
<br />
CASARETT & DOULL’S: "Tossicologia: I fondamenti dell’azione delle sostanze tossiche", 6° Edizione. Ed. EMSI, Roma. <br />
<br />
Piera Ghi: “Tossicologia: principi e applicazioni all’uso dei farmaci e dei prodotti della salute”. Edizione Minerva Medica <br />
<br />
C.L. GALLI, E. CORSINI, M. MARINOVICH “Tossicologia”. Edizione Piccin <br />
<br />
W.A. HAYES: "Principles and Methods of Toxicology", III Edition, Raven Press. <br />
<br />
GOODMAN & GILMAN’S: "The pharmacological basis of therapeutics" <br />
<br />
ERNEST HODGSON: “Tossicologia Moderna”, EdiSES <br />
Teaching methods
The oral examination will be about the entire program. Students have to show to have a good comprension of principal parts of each topic.
Assessment methods and criteria
- - -
Other information
- - -
